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SARS-CoV-2 Genomic Response Qualitative Probe (Nucleic Acid Amplification Test)

Published: August 9, 2026Updated: August 16, 2026

This test detects genetic material from the SARS-CoV-2 virus, the cause of COVID-19, using a molecular probe to confirm infection.

Quick summary

["This test helps diagnose active COVID-19 infection by checking for the virus’s genetic material in your sample."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
94642-6
Short code
SARS-CoV-2 S gene Ct Resp Qn NAA+probe
Synonyms
SARS-CoV-2 S gene Ct Resp Qn NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

How the Test Works

The test uses a specialized probe designed to target specific genetic sequences unique to SARS-CoV-2. When the probe binds to these sequences in your sample, it triggers a detectable signal, confirming the presence of the virus’s genetic material.

What to Expect Before the Test

You may receive instructions to avoid certain medications (like some antibiotics or steroids) before testing, as they could affect results. Follow your healthcare provider’s guidance closely.

Sample Collection

A healthcare professional will collect a nasal or throat swab sample. The swab is inserted into your nasal passage or throat to gather cells containing viral genetic material.

Test Results Interpretation

A positive result means the virus’s genetic material was detected, suggesting active COVID-19 infection. A negative result means no detectable genetic material was found, but this does not always rule out infection if testing was done too early.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Frequently asked questions

This test is critical for diagnosing COVID-19, guiding treatment decisions, and monitoring infection spread. It helps healthcare providers determine if you need isolation, treatment, or further testing.
A positive result indicates active infection and may require medical evaluation, isolation, or treatment. A negative result means no virus was detected at the time of testing but could still be present if symptoms develop later.
How soon can I expect results?
Results are typically available within 24 to 48 hours, depending on lab processing times. Your healthcare provider will contact you with the outcome once it’s ready.
Can I get this test at home?
Some at-home COVID-19 tests detect viral genetic material similarly, but this lab-based test is more precise for clinical use. Always follow healthcare provider guidance for testing methods.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy