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SARS-CoV-2 Nucleic Acid Detection by Qualitative Probe Assay (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test checks for genetic material from the virus that causes COVID-19 in your blood. It helps determine if you have an active infection.

Quick summary

["A COVID-19 RNA test may be used to diagnose active infection or confirm exposure to the virus."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
94640-0
Short code
SARS-CoV-2 S gene Resp Ql NAA+probe
Synonyms
SARS-CoV-2 S gene Resp Ql NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test detects the presence of SARS-CoV-2 RNA, the virus’s genetic material, using a molecular probe. This is done through a specialized lab technique that identifies fragments of the virus’s DNA or RNA even if it’s present in very small amounts.

How the Test Works

Your blood sample is taken and processed to extract viral genetic material. The lab then applies a probe that binds specifically to the virus’s RNA sequence. If the virus is present, the probe will bind, triggering a detectable signal that confirms infection.

When You Might Need This Test

This test is typically ordered if you have symptoms of COVID-19 (such as fever, cough, or shortness of breath), have been exposed to someone with COVID-19, or if you are in a setting where testing is recommended (e.g., before travel, returning from a high-risk area, or as part of routine screening).

What to Expect Before the Test

No special preparation is needed for this test. You may have a blood draw, similar to other blood tests, and you can eat and drink as usual. If you are taking certain medications, let your healthcare provider know.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

SARS-CoV-2 RNA Test (Serum/Plasma)

Frequently asked questions

How long does it take to get results from this test?
Results are usually available within 24 to 72 hours, depending on the lab’s processing time. Your healthcare provider will contact you with the results.
Can I get this test at home?
No, this test is typically performed in a clinical or laboratory setting. You will need to have a blood sample drawn by a healthcare professional.
What if I get a positive result?
If you test positive, follow your healthcare provider’s instructions for next steps, which may include isolating at home, monitoring symptoms, and possibly starting antiviral treatments if recommended. Avoid close contact with others to prevent spreading the virus.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy