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SARS-CoV-2 Genomic Sequence Detection by Qualitative Nucleic Acid Amplification Probe

Published: August 9, 2026Updated: August 16, 2026

This test detects genetic material from the virus responsible for COVID-19 using a molecular method to confirm infection.

Quick summary

["This test helps determine if you have an active COVID-19 infection by checking for the virus’s genetic material."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
96765-3
Short code
SARS-CoV-2 S gene Sal Ql NAA+probe
Synonyms
SARS-CoV-2 S gene Sal Ql NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

This test measures specific substances in your body, giving your healthcare provider a clear picture of how well certain organs and systems are working. The results help identify potential health concerns early, support an accurate diagnosis, and guide decisions about any treatment or follow-up care you may need.

The test looks for specific genetic sequences from the SARS-CoV-2 virus, which causes COVID-19. It uses a probe-based nucleic acid amplification technique to identify these sequences in a sample of your respiratory tract (e.g., nasal or throat swab).

During the test, a small sample is collected from your body and sent to a laboratory, where specialized equipment analyzes it. The lab measures the levels of particular markers in your sample, and your provider compares those values against standard reference ranges to understand what they mean for your overall health.

The test amplifies and detects tiny amounts of viral genetic material. If the virus is present, the probe binds to its genetic sequence, triggering a detectable signal. This confirms whether you are currently infected with COVID-19.

Your doctor may recommend this test if you have symptoms that point to a possible health problem, if you live with a chronic condition that needs regular monitoring, or as part of a routine checkup. It can also show whether a current treatment is working or help screen for conditions before any symptoms develop.

This test is typically ordered if you have symptoms of COVID-19 (such as fever, cough, or shortness of breath), have been exposed to someone with the virus, or if you are required for screening in certain settings (e.g., travel, healthcare visits).

Before the test, your healthcare provider will give you specific instructions to follow. Depending on the type of test, you may need to avoid eating or drinking for a set number of hours, temporarily pause certain medications or supplements, or skip strenuous exercise. Always mention every medication you take, and ask questions if any instruction is unclear.

No special preparation is needed. You will provide a sample via a nasal or throat swab, similar to a cold test. Wear a mask if possible to avoid spreading germs during the procedure.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Frequently asked questions

A positive result means you are likely infected with SARS-CoV-2 and may spread the virus to others. A negative result does not always rule out infection if testing was done too early in the illness. Follow-up testing may be recommended if symptoms persist or worsen.
How long does it usually take to get the results of this test back from my healthcare provider?
Results are usually available within 24 to 48 hours, depending on the lab’s processing time and your healthcare provider’s request for follow-up.
Can I take this test at home with a self-collection kit, or do I need to visit a lab or clinic?
Some at-home COVID-19 tests detect viral genetic material similarly, but this lab-based test is performed in a clinical setting for accuracy and safety.
Check with your insurance provider to confirm coverage, as policies vary. Your healthcare provider can also clarify costs and payment options.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy