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Serum SARS-CoV-2 IgG Antibody (Quantitative)

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of antibodies (IgG) your body produces in response to the SARS-CoV-2 virus, which causes COVID-19. IgG antibodies are part of your immune system’s long-term defense against infection.

Quick summary

["IgG antibodies help your body remember the virus for future protection after an infection has passed."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
42956-3
Short code
SARS-CoV IgM Ser Ql
Synonyms
SARS-CoV IgM Ser Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

IgG antibodies are a type of antibody your immune system creates after you’ve been exposed to the SARS-CoV-2 virus. They develop several weeks after infection and can stay in your system for months or longer, providing long-term immunity. This test helps determine if your body has produced these antibodies, which may indicate past infection.

Why Might You Need This Test?

Doctors may order this test to confirm past COVID-19 infection, assess immunity in vaccinated individuals, or evaluate immune response in people who’ve recovered from COVID-19. It’s also sometimes used in research or clinical studies to track antibody levels over time.

How Is This Test Performed?

A blood sample is taken from a vein in your arm. The sample is then sent to a lab for analysis using an immunoassay method, which detects the presence and concentration of IgG antibodies specific to SARS-CoV-2.

What Are the Possible Results?

Results are typically reported as a quantitative measurement of antibody concentration. A positive result means detectable IgG antibodies are present, suggesting past infection. A negative result means no detectable antibodies were found, which may indicate no prior infection or insufficient time since exposure.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

SARS-CoV-2 IgG Antibody

Frequently asked questions

How long does it take to get results from this test?
Results are usually available within 1 to 3 business days, depending on your lab’s processing schedule. Your healthcare provider will contact you once the results are ready.
Can I have this test if I’m currently sick with COVID-19?
No, it’s generally recommended to wait until you’ve fully recovered from COVID-19 symptoms before having this test. IgG antibody levels may be too low or unreliable during an active infection.
What does a low or undetectable antibody level mean?
A low or undetectable antibody level may suggest you either never had a significant exposure to the virus or that your immune response was weak. This doesn’t necessarily mean you’re at higher risk of future infection, but it may warrant discussion with your doctor about vaccination status or other preventive measures.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy