Skip to content

SARS-CoV-2 Nucleic Acid Detection by Qualitative Probe-Based Assay (RNA)

Published: August 9, 2026Updated: August 16, 2026

This test detects genetic material from the virus that causes COVID-19 in a sample collected from your respiratory tract.

Quick summary

["Helps determine if you have an active COVID-19 infection."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
41458-1
Short code
SARS-CoV RNA Spec Ql NAA+probe
Synonyms
SARS-CoV RNA Spec Ql NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

How the Test Works

The test uses a specialized probe to identify the virus’s genetic material (RNA) in your sample. If the virus is present, the test will confirm it through a positive result.

Sample Collection

You will provide a nasal or throat swab sample, which is sent to the lab for analysis. This sample is tested for the presence of SARS-CoV-2 RNA.

What to Expect Before the Test

No special preparation is needed. You may experience mild discomfort during sample collection, but it is quick and painless.

What the Results Mean

A positive result indicates an active COVID-19 infection. A negative result means the virus was not detected at the time of testing, but infection could still be possible if symptoms develop later.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

COVID-19 RNA Test

Frequently asked questions

What does a positive result mean?
A positive result means your test confirmed the presence of SARS-CoV-2 RNA, indicating you likely have an active COVID-19 infection. You should follow isolation guidelines and consult your healthcare provider for further guidance.
Can a negative result mean I still have COVID-19?
Yes, a negative result means the virus was not detected at the time of testing, but COVID-19 could still be present if symptoms develop later. If you have symptoms, consider retesting or seek medical advice.
How long does it take to get results?
Results are typically available within 24 hours, but timing may vary depending on lab processing times. Your healthcare provider will contact you with the results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy