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SARS-CoV-2 Antibody (Serum) – Total IgG and IgM by Turbidimetry

Published: August 9, 2026Updated: August 16, 2026

This test detects antibodies in your blood that your immune system produces in response to the SARS-CoV-2 virus, which causes COVID-19. It helps determine if you’ve been exposed to the virus, even if you didn’t get sick.

Quick summary

["This test checks for past or possible recent COVID-19 infection by measuring antibodies in your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
33974-7
Short code
SARS-CoV Urb Ab Titr Ser
Synonyms
SARS-CoV Urb Ab Titr Ser
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you’ve had symptoms of COVID-19, were exposed to someone with the virus, or if you’re in a setting where testing for past exposure is recommended. It can also help monitor immunity after vaccination or recovery.

What to Expect Before the Test

No special preparation is needed. You’ll likely have a simple blood draw from a vein in your arm. If you’re using blood thinners, let your provider know before the test.

What the Test Results Mean

Positive results indicate the presence of antibodies, suggesting you’ve likely been exposed to SARS-CoV-2. However, antibody levels can vary and may not always correlate with immunity. Negative results mean no detectable antibodies were found, but this doesn’t rule out past exposure.

How the Test Works

Blood is collected and analyzed using a method called turbidimetry, which measures how much light is blocked by antibodies in your serum. This helps determine their concentration.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Antibodies are part of your immune system’s defense. Detecting them can help confirm past infection, but they don’t guarantee immunity against future infection. Some people may develop antibodies after vaccination or natural infection, while others may not. This test is useful for research, screening, or monitoring but isn’t a substitute for current infection testing.

Short name

SARS-CoV-2 Antibody Test (Serum)

Frequently asked questions

What does a positive result mean?
A positive result means your blood contains antibodies against SARS-CoV-2, indicating you’ve likely been exposed to the virus. This doesn’t mean you’re immune to future infection, but it can provide historical context about your exposure.
Can antibodies protect me from getting COVID-19 again?
Antibodies may offer some protection, but they’re not a guarantee. Many people develop immunity after infection or vaccination, but levels can wane over time. Current immunity depends on factors like vaccination status, infection history, and overall health.
Is this test the same as a PCR test for active COVID-19?
No, this test looks for antibodies (past infection) rather than detecting the virus itself (active infection). A PCR test is used to find the virus in your body right now, while this test checks for immune system responses from a previous encounter.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy