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SARS-CoV-2 Nucleic Acid Detection by Sequencing-Linked Probe Assay (RNA)

Published: August 9, 2026Updated: August 16, 2026

This test detects genetic material from the virus responsible for COVID-19 using a specialized probe to identify its presence in your sample.

Quick summary

["Helps diagnose active COVID-19 infection by checking for the virus’s genetic material."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
33966-3
Short code
SARS-CoV Urb RNA Nose Ql NAA+probe
Synonyms
SARS-CoV Urb RNA Nose Ql NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

How the Test Works

Your sample (likely collected from a nasal or throat swab) is analyzed to detect the virus’s RNA sequence. A probe binds specifically to the virus’s genetic material if present, confirming infection.

Sample Collection

A swab is taken from your upper respiratory tract (nose or throat) to collect cells and fluids that may contain the virus. This is a quick, non-invasive procedure.

When You Might Need This Test

This test is commonly used to diagnose COVID-19, especially when symptoms are present or if you’ve been exposed to someone with the virus. It may also be used for monitoring during recovery or in certain high-risk settings.

What to Expect During Testing

You’ll likely be asked to sit quietly while a healthcare provider collects the sample. Results are typically available within 24–48 hours, depending on lab processing times.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: This test is critical for identifying active COVID-19 infection, guiding treatment decisions, and controlling outbreaks by confirming or ruling out viral presence in individuals.

Short name

SARS-CoV-2 RNA Probe Test

Frequently asked questions

Why was I asked to take this test?
Your doctor may recommend this test if you have symptoms like fever, cough, or shortness of breath, or if you’ve been exposed to someone with COVID-19. It helps determine if you need treatment or isolation.
How long will I need to isolate if my test is positive?
If your test is positive, follow your healthcare provider’s guidance on isolation and quarantine. Duration depends on symptoms and recovery, but it’s usually 5–10 days after symptom onset.
Can I get this test at home?
Some at-home COVID-19 tests detect viral RNA, but this specific test is typically performed in a clinical lab. Check with your healthcare provider for availability of similar at-home options.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy