SARS-CoV-2 Nucleic Acid Detection by Reverse Transcription Polymerase Chain Reaction (RT-PCR) in Respiratory Specimen
This test checks for the presence of genetic material from the virus that causes COVID-19 in a sample collected from your respiratory tract.
["Determines if you currently have an active COVID-19 infection."]
Key facts at a glance
- LOINC
- 33967-1
- Short code
- SARS-CoV Urb RNA SerPl Ql NAA+probe
- Synonyms
- SARS-CoV Urb RNA SerPl Ql NAA+probe
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- probe-amp-tar
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
How the Test Works
The test uses a special probe designed to detect the virus’s genetic material (RNA). A small sample of your respiratory secretions is collected and analyzed to identify the virus’s unique genetic signature.
What to Expect Before the Test
You may be asked to provide a nasal or throat swab sample. Some facilities use a nasal swab, while others may use a throat swab or a combined sample. Follow your healthcare provider’s instructions for preparation.
What to Expect During the Test
The test is typically quick and painless. You may feel mild discomfort or irritation from the swab insertion, but it usually lasts only a few seconds.
What to Expect After the Test
After the test, you can resume normal activities. If you experience discomfort, mild soreness at the site of the swab may occur and can be managed with over-the-counter pain relievers if needed.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
A positive result indicates the presence of the virus and may mean you are contagious. A negative result means the virus was not detected at the time of testing, but it does not definitively rule out infection. Repeat testing may be recommended for further evaluation, especially if symptoms persist.
Short name
COVID-19 RT-PCR Test
Frequently asked questions
Why might my doctor order this test?
What does a positive result mean?
Can I get this test at home?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy