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SARS-CoV-2 Nucleic Acid Detection by Qualitative Reverse Transcription Polymerase Chain Reaction (RT-PCR) from Specimen

Published: August 9, 2026Updated: August 16, 2026

This test checks for the genetic material (RNA) of the virus that causes COVID-19 in a sample collected from you. It helps determine if you have an active infection.

Quick summary

["This test helps healthcare providers diagnose COVID-19 and guide treatment decisions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
94647-5
Short code
SARSr-CoV RNA Spec Ql NAA+probe
Synonyms
SARSr-CoV RNA Spec Ql NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test if you have symptoms like fever, cough, shortness of breath, or a sore throat, or if you’ve been exposed to someone with COVID-19. It can also be used to screen for infection in certain settings, such as before travel or in high-risk groups.

How Is the Sample Collected?

A nasal or throat swab is taken to collect a sample. This is a quick, painless procedure that involves inserting a small swab into your nose or throat to gather cells and fluids that may contain the virus.

What Are the Possible Results?

A positive result means the test detected the virus’s RNA, suggesting you are likely infected with COVID-19. A negative result means the virus was not detected in the sample at the time of testing, but this does not always mean you are not infected. Results may vary depending on when you were tested relative to symptom onset.

What Does This Test Tell You About My Health?

This test helps determine if you have an active COVID-19 infection. It does not measure your immune response or long-term health effects from COVID-19. If you test positive, follow your healthcare provider’s advice for isolation and treatment.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: This test is critical for identifying active COVID-19 infections, enabling prompt isolation, treatment, and public health measures to control virus spread. Results guide decisions about quarantine, testing frequency, and vaccination status. While highly specific, false negatives can occur if testing is done too early or if the sample is insufficient.

Short name

SARS-CoV-2 RNA Test

Frequently asked questions

What does a positive result mean?
A positive result means your test detected the virus’s genetic material, indicating you are likely infected with COVID-19 at the time of testing. You should follow isolation guidelines and consult your healthcare provider for further advice.
Can I get this test at home?
Some at-home COVID-19 tests detect the virus’s RNA, but they are typically less sensitive than lab tests. Lab tests like this one are more reliable for confirming infection, especially in certain clinical settings. Always follow your healthcare provider’s instructions.
How soon after exposure can I get a positive result?
Symptoms may appear 2–14 days after exposure, but viral RNA may be detectable earlier. A positive result can occur as early as 2–5 days after exposure, depending on when testing is done relative to symptom onset or exposure.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy