Skip to content

SARS-CoV-2 Genomic RNA Detection by Qualitative Nucleic Acid Probe Assay

Published: August 9, 2026Updated: August 16, 2026

This test checks for the presence of genetic material from the virus that causes COVID-19 in a sample collected from your nose or throat.

Quick summary

["Determines if you may have an active COVID-19 infection."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
95823-1
Short code
SARS-rel CoV E gene Sal Ql NAA+probe
Synonyms
SARS-rel CoV E gene Sal Ql NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

How the Test Works

The test uses a special probe to detect genetic material (RNA) from the SARS-CoV-2 virus. If the virus is present, the test will confirm it by identifying these genetic sequences. This is not a test for antibodies or past infection.

What to Expect During Testing

You will provide a nasal or throat swab sample. The sample is then processed to extract viral genetic material. The test is usually done in a lab and results are reported as either positive or negative for the virus.

When This Test Is Needed

Your healthcare provider may recommend this test if you have symptoms of COVID-19, such as fever, cough, or difficulty breathing, or if you have been exposed to someone with COVID-19. It may also be used for screening in certain settings.

What the Results Mean

A positive result means the virus is detected in your sample, which may indicate an active COVID-19 infection. A negative result means the virus was not detected at the time of testing, but this does not always mean you do not have COVID-19.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: This test is critical for identifying active infections, guiding isolation and treatment decisions, and helping to control the spread of COVID-19. It is used alongside other measures like symptom assessment and public health guidelines to manage outbreaks.

Short name

COVID-19 RNA Test (Qualitative)

Frequently asked questions

What does a positive result mean?
A positive result indicates that the virus responsible for COVID-19 was detected in your sample. This suggests you may have an active infection and should follow isolation and treatment guidelines recommended by your healthcare provider.
Can a negative result mean I don’t have COVID-19?
A negative result means the virus was not detected at the time of testing, but it does not definitively rule out COVID-19. You might still be infected if the virus is present in low amounts or if the test was taken too early. Retesting may be advised if symptoms persist.
How soon after exposure can I get tested?
Testing is typically recommended 2–14 days after exposure, with the earliest reliable results usually appearing around 2–5 days post-exposure. However, symptoms may not appear until days later, so testing at the first sign of illness is also important.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy