SARS-CoV-2 Nucleic Acid Detection in Upper Respiratory Specimen (Qualitative PCR)
This test checks for the presence of genetic material from the virus that causes COVID-19 in your upper respiratory tract, such as a nasal swab or throat swab.
["Determines if you have an active COVID-19 infection by detecting the virus’s genetic material."]
Key facts at a glance
- LOINC
- 96122-7
- Short code
- SARS-rel CoV E gene Upper resp Ql NAA+prb
- Synonyms
- SARS-rel CoV E gene Upper resp Ql NAA+prb
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- probe-amp-tar
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
How the Test Works
The test uses a specialized laboratory technique called polymerase chain reaction (PCR) to identify tiny pieces of the virus’s genetic code. A small sample of your upper respiratory secretions is collected and analyzed to detect the virus’s genetic material, even if you’re not yet showing symptoms.
What to Expect Before the Test
You may be asked to avoid eating, drinking, or using mouthwash for a short time before the test. Your healthcare provider will give you specific instructions based on your situation. The test typically involves a quick, painless swab of your nose or throat.
What to Expect During the Test
The procedure is quick and usually done in a doctor’s office, clinic, or testing center. You may feel mild discomfort from the swab, but it’s not invasive. The sample is then sent to a lab for analysis.
When You Might Need This Test
This test is often recommended if you have symptoms of COVID-19, such as fever, cough, or shortness of breath, or if you’ve been exposed to someone with the virus. It may also be used for screening in settings like schools, workplaces, or community gatherings.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
COVID-19 Upper Respiratory PCR Test
Frequently asked questions
Why might I get this test?
What does a positive result mean?
Can a negative result mean I don’t have COVID-19?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy