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: Staphylococcus aureus DNA, Nasal Swab, Nucleic Acid Probe

Published: August 9, 2026Updated: August 16, 2026

: This test detects the genetic material (DNA) of Staphylococcus aureus, a common bacterium, in a sample taken from the inside of the nose. It is used to identify people who carry the bacteria without necessarily having an infection.

Quick summary

[": A positive result means S. aureus bacteria were detected in the nasal sample, indicating carriage of the organism."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
92701-2
Short code
S aureus DNA Nose Ql NAA+probe
Synonyms
S aureus DNA Nose Ql NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

: What This Test Detects

: The test looks for DNA specific to Staphylococcus aureus, including both antibiotic-susceptible and antibiotic-resistant strains depending on the assay used. Because it targets genetic material, it can identify the bacterium even when very few organisms are present. The sample is collected with a swab from the front part of the nostrils.

: Why Nasal Screening Is Done

: The nose is a common place where S. aureus lives harmlessly as part of the normal flora. Screening the nose is often done before certain surgeries or in healthcare settings to identify carriers, so that steps can be taken to reduce the risk of the bacteria causing a wound or bloodstream infection later. It may also be used as part of infection-control programs.

: How the Sample Is Collected

: A healthcare professional gently rotates a soft swab inside one or both nostrils. The swab is then sent to the laboratory, where a molecular method such as a nucleic acid probe or polymerase chain reaction (PCR) is used to look for S. aureus DNA. Collection is quick and generally not painful.

: Understanding Your Result

: A positive result indicates that S. aureus DNA was found in the nasal sample, meaning you are likely a carrier. A negative result means the DNA was not detected at the time of testing. Results are interpreted together with your medical history and the reason the test was ordered; your clinician will explain what they mean for your care.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

: S. aureus Nasal PCR

Frequently asked questions

: Does a positive result mean I have an infection?
: No. A positive result usually means you are carrying the bacteria in your nose, which many healthy people do without any illness. Your clinician will determine whether an infection is present based on your symptoms and other findings.
: Can the test tell which antibiotics will work?
: Standard nasal screening tests for S. aureus DNA confirm the presence of the organism but do not always identify antibiotic resistance. If resistance information such as MRSA status is needed, a specific assay or additional testing may be required, and your clinician will interpret the results accordingly.
: Do I need to prepare for the test?
: Usually no special preparation is needed. Follow any instructions from your healthcare provider about the timing of the swab, especially if you are being screened before surgery or are using nasal medications.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy