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Staphylococcus aureus detection by nucleic acid probe (urine)

Published: August 9, 2026Updated: August 16, 2026

This test checks for the presence of genetic material from *Staphylococcus aureus*—a common bacteria that can cause infections—using a urine sample. It helps identify infections that may require treatment.

Quick summary

["Detects bacterial infection in urine with a simple probe test."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
103198-8
Short code
S aureus DNA Resp Ql NAA+probe
Synonyms
S aureus DNA Resp Ql NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you have symptoms like frequent urination, pain during urination, or signs of a urinary tract infection (UTI). It’s also used in certain hospital settings to quickly screen for infections caused by *Staphylococcus aureus* in urine.

How the Test Works

A small urine sample is collected and tested using a specialized probe that targets genetic material unique to *Staphylococcus aureus*. If the bacteria’s DNA is present, the test detects it and confirms possible infection.

Sample Collection

You’ll likely provide a midstream urine sample (midstream catch) or a clean-catch sample. Follow your provider’s instructions to ensure accuracy.

What to Expect

The test is quick and painless. Results are often available within hours, depending on lab processing. No special preparation is needed beyond standard hygiene.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Positive results suggest a urinary tract infection caused by *Staphylococcus aureus*, which may require antibiotics. Negative results mean no detectable bacteria in the sample, but further testing may still be needed if symptoms persist. This test helps guide treatment decisions and monitor infection spread in healthcare settings.

Short name

Urine *Staph aureus* probe test

Frequently asked questions

How long does it take to get results?
Results are typically available within 24 hours, depending on lab workflow. Your provider will discuss the timing with you before ordering the test.
Can I drink water before the test?
Yes, you can drink water as usual unless instructed otherwise. Avoid excessive fluids that might dilute the sample if your provider specifies a clean-catch method.
Does this test replace a urine culture?
No, this probe test is a rapid screening tool. A urine culture remains the gold standard for identifying bacterial infections and antibiotic resistance, so your provider may recommend both tests depending on your symptoms and needs.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy