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Serum/plasma substance concentration (qualitative) for bile acids

Published: August 9, 2026Updated: August 16, 2026

This test measures the presence or absence of bile acids in your blood, which helps assess liver function and bile flow.

Quick summary

["Bile acids help your body digest fats and signal liver health."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
23933-5
Short code
S aureus Etx B Spec Ql
Synonyms
S aureus Etx B Spec Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like jaundice (yellowing of skin/eyes), unexplained fatigue, abdominal pain, or if they suspect liver disease, bile duct blockage, or metabolic disorders like pruritus (itching) related to bile acid malabsorption.

What to Expect Before the Test

No special preparation is typically needed, but you may be asked to fast for 8–12 hours before the draw if your lab uses a specific method. Bring any medications or supplements you’re currently taking to discuss with your provider.

During the Test Process

A healthcare professional will draw blood from a vein in your arm. The process takes a few minutes, and you may feel a brief pinch. The blood sample is sent to the lab for analysis.

What the Results Mean

A positive (detected) result indicates elevated bile acids, which may signal liver disease, bile duct issues, or other metabolic conditions. A negative result means no detectable bile acids were found in your sample. Results are interpreted in the context of your symptoms and medical history.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Frequently asked questions

How bile acids are processed in the liver and intestines can reflect underlying conditions like cirrhosis, cholestasis (bile obstruction), or rare genetic disorders. Elevated levels may also be linked to pruritus (severe itching) or metabolic syndrome.
This test is qualitative, so it only tells whether bile acids were present or not—not their exact concentration. It’s often used as a screening tool rather than a diagnostic alone.
What if I have a positive result?
If bile acids are detected, your provider may order additional tests (e.g., liver function panels, imaging) to pinpoint the cause. Treatment depends on the underlying issue, which could include dietary changes, medications, or further medical evaluation.
Can diet affect this test?
Yes, certain foods (e.g., high-fat meals) may temporarily alter bile acid levels, so fasting guidelines are critical. Always follow your provider’s instructions to ensure accurate results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy