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Serum or Plasma Substance Concentration by Immunoassay (e.g., for C-reactive protein or similar inflammatory marker)

Published: August 9, 2026Updated: August 17, 2026

This test measures levels of certain proteins in your blood that can signal inflammation or immune system activity. It helps doctors assess conditions like infections, autoimmune diseases, or other health concerns.

Quick summary

["Inflammation and immune response levels may be monitored with this test."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
102909-9
Short code
S aureus Etx C IgE RAST
Synonyms
S aureus Etx C IgE RAST
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
10
Ref high
40
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
rast
CPT
84484
SNOMED
302774002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

This test detects specific proteins in your serum or plasma that are produced in response to inflammation or immune activity. The exact proteins measured depend on the lab’s specific panel, but they often include markers like C-reactive protein (CRP) or others that reflect your body’s reaction to injury, infection, or disease.

Why It’s Done

Your healthcare provider may order this test to evaluate symptoms such as fever, joint pain, swelling, or unexplained fatigue. It can also be used to monitor chronic conditions like arthritis, heart disease, or infections.

Common Uses

Common reasons include diagnosing infections (e.g., bacterial or viral), checking for autoimmune diseases (e.g., rheumatoid arthritis), assessing heart attack risk, or monitoring treatment progress for conditions like lupus or kidney disease.

Sample Collection and Preparation

A blood sample is drawn from a vein, typically in your arm. The blood is then processed to separate serum (liquid part after clotting) or plasma (liquid part after anticoagulant use). The test analyzes these fluids for protein markers.

Reference range

Adult: 10-40 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Inflammatory Marker Profile

Frequently asked questions

How long does it take to get my results?
Results are usually available within 24 to 48 hours, depending on lab processing times. Your doctor will discuss them with you during your follow-up visit.
What do elevated or low levels mean?
Elevated levels may indicate inflammation, infection, or autoimmune activity, while low levels could suggest suppressed immune function or other underlying issues. Your doctor will interpret results in the context of your symptoms and medical history.
Can I fast before this test?
No fasting is required for this test, as it measures proteins in your blood that don’t depend on recent food intake. However, always follow your doctor’s specific instructions.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy