Understanding Your Laboratory Test: A Complete Patient Guide to Testing, Sample Collection, and Interpreting Your Results
This test checks for the presence of the toxic shock syndrome toxin gene in Staphylococcus aureus bacteria using advanced DNA detection methods.
{"Detects the gene that causes toxic shock syndrome toxin in Staphylococcus aureus","Uses a blood sample to identify if the bacteria carries the toxin gene","Helps diagnose toxic shock syndrome, a rare but serious condition","Results help doctors determine if antibiotics targeting the toxin are needed","Sample is collected from blood (serum)"}
Key facts at a glance
- LOINC
- 44881-1
- Short code
- STAP TSS TOX
- Synonyms
- S aureus TSST gene Spec Ql NAA+probe
- Category
- cardiac
- Sample
- serum
- Container
- Serum separator tube (SST) or red-top tube
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 0–120 years
- Method
- probe-amp-tar
- CPT
- 87641
- SNOMED
- 12244009
- Specimen volume
- 2-5 mL of venous blood
- Stability
- Store at 2-8°C if processed within 24 hours; freeze at -70°C for longer storage. Avoid repeated freeze-thaw cycles.
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 24–72 hours
- Order
- routine
This test is a laboratory analysis performed on a sample of your blood, urine, or other body fluid or tissue. It allows your healthcare provider to measure specific substances in your body, check how certain organs are functioning, and gather important information that supports accurate diagnosis and good medical decision-making about your overall health.
This test looks for the toxic shock syndrome toxin gene (TSST-1) in Staphylococcus aureus bacteria. It uses a method called nucleic acid amplification (NAA) with probe detection, which is very sensitive and can find even small amounts of the genetic material. The test is performed on a serum sample, which is the liquid part of your blood after it clots.
Your doctor may order this test as part of a routine checkup, to help diagnose a new medical condition, to monitor an illness you already have, or to see how well a current treatment is working. The results can also reveal health problems early, sometimes before you notice any symptoms, so that care can begin promptly.
Your doctor may order this test if you have symptoms of toxic shock syndrome (TSS), such as high fever, rash, low blood pressure, or multi-organ failure. TSS is a rare but life-threatening condition that can occur from certain Staphylococcus aureus infections, often associated with tampon use, surgical wounds, burns, or skin infections. This test helps confirm whether the bacteria causing your infection can produce the dangerous toxin.
The sample is usually collected at a laboratory, hospital, or your provider's office. A blood sample is drawn from a vein in your arm using a small needle, while urine or other samples are collected in a sterile container. The entire procedure is quick, typically taking only a few minutes, and a trained staff member will guide you through each step.
A healthcare professional will draw a small amount of blood from a vein in your arm. The blood is collected into a tube and allowed to clot. The serum (liquid part) is then separated and tested in a laboratory using special equipment to detect the toxin gene.
Your results will show whether the measured values fall within the normal reference range for someone of your age and sex. Abnormal results do not always mean you have a serious condition, since factors such as medications, diet, hydration, or recent illness can affect them. Your provider will review the findings with you and recommend any follow-up testing or treatment if needed.
A positive result means the Staphylococcus aureus bacteria found in your sample carries the toxic shock syndrome toxin gene. This suggests your infection may be capable of producing the toxin that causes TSS. A negative result means the toxin gene was not detected, though this does not completely rule out infection. Your doctor will interpret these results along with your symptoms and other test findings.
This test is very safe. If blood is drawn, you may feel a brief sting or notice slight bruising or soreness at the needle site, which usually fades within a day or two. Serious complications such as infection or excessive bleeding are rare. Let your provider know in advance if you have a bleeding disorder or take blood-thinning medications.
The risks are minimal and similar to routine blood tests. You may feel slight pain or bruising at the needle site, and in rare cases, infection or excessive bleeding may occur. The test itself poses no additional risks.
Reference range
Not detected - Negative for Staphylococcus aureus toxic shock syndrome toxin (tst) geneN/A
No special preparation required. Inform clinician of recent antibiotic use as this may affect test results.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
This test is clinically significant because toxic shock syndrome is a medical emergency that can lead to organ failure and death if not treated promptly. Identifying the toxin gene helps doctors confirm the diagnosis and choose appropriate treatment, including specific antibiotics that target toxin-producing bacteria. The test is particularly valuable when traditional cultures are negative but clinical suspicion of TSS remains high, as the toxin gene can be detected directly from patient specimens.
Frequently asked questions
Is toxic shock syndrome the same as sepsis?
How long does it take to get results?
Can I have this test if I'm pregnant?
Do I need to fast before this test?
What happens if my test is positive?
Sources
- 1
- 2
- 3LOINC Code ReferenceSource
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy