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Bromocresol Green Protein Electrophoresis (BCG Protein Electrophoresis)

Published: August 9, 2026Updated: August 16, 2026

This test measures protein distribution in your blood using an electrophoresis method with bromocresol green dye to assess albumin and globulin levels.

Quick summary

["This helps diagnose conditions affecting protein balance in your bloodstream."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
100788-9
Short code
S botryosum IgG4-mCnc
Synonyms
S botryosum IgG4-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

Electrophoresis separates blood proteins based on size and charge. Bromocresol green dye binds to albumin, which appears as a distinct band in the test results. This helps distinguish between albumin and globulin fractions, which can indicate imbalances in your immune system or kidney function.

Why It’s Done

Doctors may order this test to evaluate conditions like chronic kidney disease, liver disease, or certain immune disorders. It can also help monitor protein loss due to kidney problems or check for abnormal protein production.

Common Uses in Healthcare

This test is less common than general protein panels but is useful in specialized cases where detailed protein fraction analysis is needed, such as assessing nephrotic syndrome or evaluating protein malnutrition.

Sample Collection and Preparation

A blood sample is drawn from a vein, typically in your arm. The sample is processed and sent to a lab for electrophoresis with bromocresol green dye. Results are interpreted based on protein bands and their relative densities.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

BCG Protein Electrophoresis

Frequently asked questions

How might my results affect my treatment?
Low albumin levels (reduced band intensity) may signal kidney disease, liver issues, or malnutrition. High globulin levels could indicate chronic infections, autoimmune disorders, or inflammation. Your healthcare provider will discuss findings in the context of your symptoms and medical history.
What do abnormal results mean?
Abnormal results may prompt further testing, such as additional protein electrophoresis, kidney function tests, or imaging studies to identify the underlying cause. For example, a low albumin-to-globulin ratio might suggest kidney disease, while high globulin levels could point to immune-related conditions.
Can I prepare for this test?
No special preparation is needed. Avoid heavy meals before the draw, but hydration is encouraged. If you’re on certain medications (e.g., diuretics), discuss this with your provider to ensure accurate results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy