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Serum Creatinine (from whole blood)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of creatinine, a waste product from muscle metabolism, in your blood. It helps assess kidney function.

Quick summary

["A creatinine test helps doctors check how well your kidneys are filtering waste from your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
105799-1
Short code
S. capitis+S. hominis DNA Ct Bld +Qn
Synonyms
S. capitis+S. hominis DNA Ct Bld +Qn
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Matters

Creatinine is a byproduct of muscle breakdown and is filtered out by your kidneys. High levels may indicate kidney problems, while low levels could suggest muscle disorders or dehydration. Your doctor may order this test to monitor kidney health, especially if you have conditions like diabetes or high blood pressure.

What to Expect Before the Test

No special preparation is needed for this blood test. You may have a small needle inserted into your arm to draw blood. If you’re on a low-protein diet or have recently exercised, let your doctor know—these can affect results.

What the Results Mean

Results are typically reported in milligrams per deciliter (mg/dL). While reference ranges vary by lab, elevated levels may signal reduced kidney function, while very low levels could raise concerns about muscle metabolism or hydration status. Your doctor will interpret results in the context of your overall health.

Common Causes of Abnormal Results

High creatinine levels may be due to kidney disease, dehydration, or severe muscle damage. Low levels could result from muscle wasting, liver disease, or overhydration. Other factors like certain medications or kidney disorders can also influence results.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Creatinine levels are a key indicator of kidney function, often used alongside other tests like blood urea nitrogen (BUN) to diagnose or monitor kidney disease. Regular monitoring helps detect early signs of kidney problems, which can be managed with lifestyle changes or medical treatment.

Short name

Creatinine Level

Frequently asked questions

Why might my creatinine level be higher than usual?
Possible causes include kidney disease, dehydration, severe muscle injury, or conditions like heart failure or diabetes that put extra strain on your kidneys. If you notice unexplained changes, discuss them with your doctor.
Could diet affect my creatinine test results?
Yes, high-protein diets or recent intense exercise can temporarily raise creatinine levels. Low-protein diets or muscle loss (e.g., from illness) may lower them. Your doctor may adjust your diet or timing if needed.
What should I do if my creatinine test is abnormal?
Follow your doctor’s advice for next steps, which may include additional tests, lifestyle changes (like staying hydrated), or treatment for underlying conditions. Never delay seeking care if you suspect kidney issues.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy