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Serum Creatinine Concentration (Standard Method)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of creatinine, a waste product from muscle metabolism, in your blood serum. It helps assess kidney function.

Quick summary

["Your kidneys filter waste from blood; high creatinine levels may signal impaired kidney function."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
80153-0
Short code
sCD27 CSF-aCnc
Synonyms
sCD27 CSF-aCnc
Category
chemistry
Sample
csf
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

Why This Test Is Done

Doctors may order this test to check for kidney problems, monitor kidney disease progression, or evaluate kidney function before certain treatments. It’s also used to monitor patients with conditions like diabetes or heart disease that can affect kidney health.

What to Expect Before the Test

No special preparation is needed, but you may be asked to fast for 8–12 hours before the test if it’s part of a broader metabolic panel. Hydration is usually encouraged unless instructed otherwise.

How the Test Is Performed

A blood sample is drawn from a vein, typically in your arm, by a healthcare professional. The sample is sent to a lab for analysis.

Possible Results and Their Meaning

Results are compared to standard reference ranges, though exact values can vary by lab. High levels may indicate reduced kidney function, while low levels could suggest muscle disorders or dehydration.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Creatinine levels are a key indicator of kidney function. Elevated levels often signal impaired filtration, which can lead to complications like fluid buildup, electrolyte imbalances, or worsening of chronic kidney disease. Regular monitoring helps manage these risks.

Short name

Creatinine (Serum)

Frequently asked questions

What causes creatinine levels to be higher than normal?
Higher-than-normal creatinine levels may result from reduced kidney function, dehydration, severe muscle damage, or certain medications. Conditions like diabetes or heart disease can also contribute.
What should I do if my creatinine level is elevated?
If your test results show elevated creatinine, your doctor may recommend lifestyle changes (like hydration and diet adjustments), further testing, or treatments to manage underlying conditions affecting kidney function.
Can diet affect creatinine levels?
Dietary protein intake can influence creatinine levels, but the impact is indirect—high protein intake increases muscle breakdown, which may temporarily raise creatinine. Your doctor will consider overall health when interpreting results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy