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Serum or Plasma Sodium (Substance Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of sodium, a key electrolyte, in your blood or plasma. Sodium helps regulate fluid balance and nerve/muscle function.

Quick summary

Sodium levels help doctors check if you’re retaining or losing too much fluid or have conditions like high blood pressure or kidney issues.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
94416-5
Short code
SCN1A c.603-91G>A Geno Bld/T
Synonyms
SCN1A c.603-91G>A Geno Bld/T
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
molgen
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why Sodium Levels Matter

Sodium is essential for maintaining proper fluid balance in your body. Too much sodium can lead to dehydration, high blood pressure, or swelling, while too little can cause confusion, muscle cramps, or irregular heartbeat. Your doctor may order this test if you have symptoms like excessive thirst, swelling, or unexplained weight changes.

What to Expect Before the Test

No special preparation is needed for this test. You may have a small needle inserted into your arm or finger to draw blood, or your doctor may collect plasma from a blood draw. If you’re tested for urine sodium, you may need to collect a sample at home or in a lab.

What the Results Mean

Results are compared to a standard range for healthy adults, though your doctor will interpret them based on your overall health and symptoms. Very high or very low sodium levels can signal underlying health issues that need medical attention.

Common Causes of Abnormal Results

High sodium levels (hypernatremia) can occur from dehydration, excessive salt intake, or conditions like diabetes insipidus. Low sodium levels (hyponatremia) may result from kidney problems, excessive sweating, or overuse of diuretics.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Abnormal sodium levels are often a red flag for conditions like heart disease, kidney dysfunction, or hormonal imbalances. Your doctor may monitor sodium levels regularly if you have chronic conditions like heart failure, liver disease, or certain medications that affect fluid balance.

Short name

Sodium Level

Frequently asked questions

What triggers a sodium test?
A sodium test may be ordered if you have symptoms like confusion, swelling, rapid heartbeat, or unexplained weight gain/loss. Doctors also check sodium levels in patients with kidney disease, heart failure, or those taking medications that affect sodium balance.
How long does it take to get results?
Results are typically available within 1–3 business days, depending on your lab’s processing time. Your doctor will discuss the findings with you during your follow-up visit.
Can I eat or drink before the test?
No special diet is required, but avoid excessive salt intake 24 hours before testing if instructed by your doctor. For urine sodium tests, follow any specific instructions provided.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy