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Serum or Plasma Substance Concentration (Bromocresol Green Dye Binding)

Published: August 9, 2026Updated: August 16, 2026

This test measures how bromocresol green dye binds to a protein in your blood, often used to assess liver function or protein synthesis.

Quick summary

["Helps evaluate liver health and protein balance in your bloodstream."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
105598-7
Short code
SDHA & SDHB & SDHC & SDHD mut anl Tiss
Synonyms
SDHA & SDHB & SDHC & SDHD mut anl Tiss
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
molgen
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test uses bromocresol green dye, which binds to albumin and other proteins in your serum or plasma. The amount of dye bound reflects protein levels, particularly albumin, which is important for maintaining blood volume and transporting other substances.

Why It Matters in Medicine

Abnormal results may indicate liver disease, malnutrition, or conditions affecting protein production, such as kidney problems or certain cancers.

Common Uses and Indications

Doctors may order this test to monitor liver function, check for protein deficiencies, or assess the effectiveness of treatments for conditions like cirrhosis or kidney disease.

Sample Collection and Preparation

A blood sample is drawn from a vein, typically in the arm. The sample is processed to separate serum (if drawn without anticoagulants) or plasma (if drawn with anticoagulants like EDTA or citrate).

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

BCG Dye Binding Test

Frequently asked questions

What might cause abnormal results?
Low levels of dye binding could suggest liver disease, severe malnutrition, or conditions that reduce protein synthesis, such as nephrotic syndrome or certain cancers. High levels may rarely indicate overproduction of proteins or lab artifacts.
How long will results take to return?
Results are usually available within 1 to 3 business days, depending on lab processing times and your healthcare provider’s workflow.
Is fasting required for this test?
No fasting is typically required for this test, as it measures protein binding and does not rely on dietary factors.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy