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Sebacate-to-Creatinine Ratio, Urine

Published: August 9, 2026Updated: August 16, 2026

Measures urine sebacate relative to creatinine, helping account for differences in urine concentration during evaluation of fatty acid and peroxisomal metabolism.

Quick summary

["This test measures a metabolic marker in urine after adjusting for urine concentration."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
25134-8
Short code
Sebacate/Creat Ur-sRto
Synonyms
Sebacate/Creat Ur-sRto
Category
kidney
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

This test measures the amount of sebacate, a fatty-acid metabolism marker, relative to creatinine in a urine sample. The ratio helps account for how concentrated or dilute the urine is.

Why might I need this test?

It may be used in the evaluation of suspected inherited disorders involving fatty acid oxidation, mitochondria, or peroxisomes. It is generally interpreted as part of a broader metabolic workup rather than as a stand-alone diagnosis.

How is the test performed?

A urine specimen is collected and analyzed in the laboratory. The laboratory measures sebacate and creatinine and reports their ratio.

How do I prepare for the test?

No special preparation is usually required unless your clinician gives specific collection instructions. Follow the provided directions for collection timing, container, storage, and delivery to the laboratory.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Urine sebacate-to-creatinine ratio

Frequently asked questions

Why is creatinine included in this urine test?
Creatinine is used to adjust the sebacate measurement for differences in urine concentration. This makes results more comparable between samples.
Does an abnormal result confirm a metabolic disorder?
No. An abnormal ratio can suggest a problem with fatty acid or peroxisomal metabolism, but it does not diagnose a specific disorder by itself.
How is the urine sample collected?
The sample is collected using the container and schedule provided by the laboratory or clinician. Certain tests may require a timed collection, so follow the instructions exactly.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy