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Serum or Plasma Concentration of Secobarbital (Mass Concentration)

Published: August 9, 2026Updated: August 17, 2026

This test measures the amount of secobarbital, a barbiturate medication, in your blood. It’s often used to check drug levels in cases of overdose, poisoning, or therapeutic drug monitoring.

Quick summary

["This test helps assess exposure to secobarbital, a sedative-hypnotic drug, for medical decision-making."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
12489-1
Short code
Secobarbital Gast Ql
Synonyms
Secobarbital Gast Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
10
Ref high
40
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84484
SNOMED
302774002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test if you’ve been exposed to secobarbital (e.g., accidental overdose, intentional misuse, or suspected poisoning). It can also be used to monitor levels in patients on long-term therapy, though this is less common for secobarbital due to its short half-life and risks.

What Does the Result Indicate?

High levels may suggest recent exposure, overdose, or improper dosing. Very low or undetectable levels indicate little to no presence of the drug in your system. Results are not used alone for diagnosis but are part of a broader evaluation.

Sample Collection and Preparation

A blood sample is drawn from a vein, typically in your arm. The sample is sent to a lab where it is processed to separate serum or plasma for testing. Secobarbital is measured using a sensitive analytical method, often high-performance liquid chromatography (HPLC) or immunoassay.

What to Expect Before the Test

No special preparation is needed, but inform your provider about all medications, supplements, or recent illnesses. Avoid eating or drinking for 8–12 hours before the test if instructed, though this is less critical for blood draws.

Reference range

Adult: 10-40 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated secobarbital levels can indicate acute poisoning, which may require immediate medical attention, including supportive care or antidotes. Chronic exposure at therapeutic doses is rare due to the drug’s short half-life and high toxicity. Results guide treatment decisions, such as monitoring for respiratory depression or adjusting care in critical cases.

Short name

Secobarbital Level

Frequently asked questions

How long does it take to get results?
Results are typically available within 1–3 business days, depending on lab processing times. Your healthcare provider will contact you once they are ready.
What if my results are abnormal?
If levels are high, your provider may recommend further evaluation, such as monitoring symptoms, adjusting treatment, or seeking emergency care. If levels are low, no immediate action is usually needed unless you suspect recent exposure.
Can I take this test at home?
No, this test requires a blood sample collected by a healthcare professional in a clinical setting. Home drug testing kits are not reliable for medical interpretation.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy