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Serum or plasma concentration of secobarbital (barbiturate metabolite)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of secobarbital, a barbiturate drug, in your blood. Secobarbital is used historically for sedation and anesthesia but is rarely prescribed today due to risks.

Quick summary

["Your blood test helps assess if you’ve been exposed to secobarbital, which may be relevant in cases of overdose or accidental ingestion."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
72928-5
Short code
Secobarbital Ur-sCnc
Synonyms
Secobarbital Ur-sCnc
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Is Done

Doctors may order this test if you’ve experienced symptoms like drowsiness, confusion, or slowed breathing that could be linked to barbiturate exposure. It may also be used in legal cases, toxicology evaluations, or monitoring for drug-related health risks.

What to Expect Before the Test

No special preparation is needed. You’ll provide a blood sample (usually from a vein in your arm) or, less commonly, a urine sample. If you’re taking other medications, let your healthcare provider know.

What the Results Mean

High levels of secobarbital may indicate recent ingestion or exposure, which can be life-threatening. Very low or undetectable levels suggest no recent exposure. Results are interpreted by your doctor based on your symptoms and medical history.

Possible Causes of Abnormal Results

Elevated levels can result from accidental poisoning, intentional overdose, or exposure to contaminated substances. Low levels may occur if the drug has already left your system or if you’re metabolizing it quickly.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Secobarbital Level (Screen/Confirm)

Frequently asked questions

What questions might you have about this test?
This test is primarily used in emergency or forensic settings to confirm barbiturate presence. It’s not typically part of routine health monitoring unless you’ve had recent exposure or symptoms.
Will I need to fast before this test?
No fasting is required, but avoid eating or drinking heavily before your blood draw to ensure accurate results. If you’re unsure, ask your healthcare provider.
Can I stop taking secobarbital before this test?
If you’re currently taking secobarbital or another barbiturate, inform your doctor before testing. Stopping medication abruptly can be dangerous, so they’ll guide you on timing and safety.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy