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Selenium/Creatinine Ratio, Urine

Published: August 9, 2026Updated: August 16, 2026

A urine test that compares selenium with creatinine to help assess selenium levels and urinary excretion.

Quick summary

["This ratio helps evaluate selenium status while accounting for how concentrated the urine sample is."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
110349-8
Short code
Selenium/Creat Msmt Ur
Synonyms
Selenium/Creat Msmt Ur
Category
kidney
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

This test measures selenium and creatinine in a urine sample. The selenium-to-creatinine ratio adjusts the selenium result for urine concentration, which can vary with fluid intake.

Why might I need this test?

A clinician may order this test to evaluate selenium exposure or nutritional status. It may be used in people with low or excessive selenium levels, certain occupations, or exposure to supplements, foods, or industrial sources containing selenium.

How is the test performed?

A urine sample is collected and analyzed in a laboratory to measure selenium and creatinine. The laboratory then calculates the selenium-to-creatinine ratio. Your clinician will determine whether a single sample or a timed collection is appropriate.

How do I prepare for the test?

Follow the collection instructions provided by your healthcare professional. If timed urine collection is required, collect all urine for the specified period and keep the container tightly closed and refrigerated if instructed. Your clinician will advise you about selenium supplements and other exposures before collection.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

A low ratio may be associated with inadequate selenium intake or poor selenium status, although diet and other factors can influence the result. A high ratio may indicate increased selenium exposure or, less commonly, impaired processing or elimination of selenium. Results should be interpreted with symptoms, medical history, diet, supplement use, and other laboratory tests.

Short name

Urine selenium-to-creatinine ratio

Frequently asked questions

What does the selenium-to-creatinine ratio show?
It estimates urinary selenium relative to urine concentration. This makes results easier to compare when urine is more or less concentrated.
Should I stop taking selenium supplements before this test?
Do not stop supplements unless your clinician specifically instructs you to. Tell the laboratory about supplement use because it can affect the result.
Does an abnormal result mean I have a selenium deficiency or toxicity?
Not by itself. Your clinician will interpret the ratio along with your diet, exposure history, symptoms, and other tests.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy