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Selenium in Serum (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of selenium, a trace mineral essential for thyroid function, antioxidant protection, and immune health, found in your blood serum.

Quick summary

["Selenium helps support your body’s natural defenses and metabolism."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
54925-3
Short code
Selenium Smn-mCnc
Synonyms
Selenium Smn-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like fatigue, hair loss, or muscle weakness, or if you have conditions like thyroid disorders, autoimmune diseases, or chronic kidney disease. It may also be part of routine screening for selenium deficiency or monitoring in certain medical treatments.

What to Expect Before the Test

No special preparation is needed for this blood test. You may have a small needle inserted into your arm to draw blood, and you can eat and drink normally before the procedure. If you’re on blood thinners, let your provider know before the test.

What the Results Mean

Results are typically reported as a mass concentration of selenium in the serum. While reference ranges vary by lab, low levels may indicate deficiency, while very high levels could signal toxicity or certain medical conditions. Your provider will interpret results in the context of your overall health.

Common Conditions Linked to Selenium Levels

Low selenium levels may be associated with weakened immunity, thyroid dysfunction, or muscle weakness. High levels can sometimes point to selenium poisoning or underlying health issues like liver disease. This test alone doesn’t diagnose conditions but helps guide further evaluation.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Selenium Level

Frequently asked questions

How often do I need this test?
The frequency depends on your health status. Routine adults may not need this test unless recommended by a provider. Those with known deficiencies, thyroid disorders, or specific risk factors (e.g., malabsorption) may need monitoring more often.
What if my results are outside the normal range?
If your selenium level is low, your provider may suggest dietary changes, supplements (under medical supervision), or further testing to check for underlying causes like poor absorption or other deficiencies. High levels may prompt investigation into potential toxicity or related conditions.
Does diet affect selenium test results?
Yes, selenium intake from foods like nuts, fish, and whole grains can influence results. Avoid extreme dietary changes before testing, but no special preparation is required for accuracy.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy