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Neutrophil count (absolute) in serum/plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the number of neutrophils, a type of white blood cell, in your blood. Neutrophils help fight infections.

Quick summary

["Neutrophils protect your body from bacterial infections; low or high levels may signal health concerns."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
98642-2
Short code
Sensory NC Pnl R MACN
Synonyms
Sensory NC Pnl R MACN
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to check for infections, blood disorders, or immune system issues. It’s also used to monitor conditions like leukemia, autoimmune diseases, or after treatments like chemotherapy.

What to Expect Before the Test

No special preparation is needed. A blood sample is taken from a vein, usually in your arm. You may feel a slight pinch, but it’s quick and painless. If you’re on blood thinners, let your provider know before the test.

What the Results Mean

Results are reported as the number of neutrophils per microliter (cells/µL) of blood. Very high or very low counts can indicate different health problems, such as infections, inflammation, or certain cancers.

Common Conditions Affecting Neutrophil Count

Low neutrophil counts (neutropenia) may occur due to infections, bone marrow disorders, or medications. High neutrophil counts (neutrophilia) can happen with infections, stress, or certain diseases like rheumatoid arthritis.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Absolute Neutrophil Count (ANC)

Frequently asked questions

What causes a low neutrophil count?
Low neutrophil counts can result from infections, certain medications (like chemotherapy), autoimmune diseases, or conditions affecting bone marrow production of blood cells.
What causes a high neutrophil count?
High neutrophil counts often appear during infections, inflammation, or stress. They can also be seen in conditions like rheumatoid arthritis or certain cancers.
Can diet affect neutrophil counts?
Diet alone rarely changes neutrophil counts significantly, but poor nutrition or vitamin deficiencies (like B12 or folate) may indirectly impact blood cell production. Always follow your provider’s advice for dietary needs.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy