Neutrophil count in cerebrospinal fluid (CSF) by automated cell differential

Why This Test Is Done

Your doctor may order this test if you have symptoms like severe headaches, neck stiffness, fever, confusion, or neurological issues. It’s often used to investigate conditions such as meningitis, encephalitis, or other infections/inflammations in the central nervous system.

What to Expect Before the Test

You’ll likely have a lumbar puncture (spinal tap) where a small needle is inserted into your lower back to collect CSF. The procedure is usually quick and done in a hospital setting. You may feel mild discomfort, but it’s generally well-tolerated.

What the Results Mean

Elevated neutrophil counts in CSF often indicate an infection (e.g., bacterial meningitis) or severe inflammation. Lower counts may suggest viral infections, autoimmune conditions, or other neurological disorders. Your doctor will interpret results in the context of your symptoms and medical history.

Common Conditions This Test Helps Diagnose

This test is critical for diagnosing infections like bacterial meningitis, abscesses in the brain, or other inflammatory conditions affecting the central nervous system. It can also help rule out conditions like multiple sclerosis or other neurological disorders.