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Epidermal keratinocyte DNA (fluid) – quantitative probe

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of DNA derived from skin cells found in your body fluids, such as blood or urine. It may be used to detect certain genetic or cellular changes.

Quick summary

["This test helps assess skin-related conditions or genetic markers in body fluids."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
106602-6
Short code
S epidermidis DNA Fld Ql NAA+n-prb
Synonyms
S epidermidis DNA Fld Ql NAA+n-prb
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
non-probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is This Test Measuring?

The test focuses on DNA fragments originating from epidermal keratinocytes (skin cells). These DNA fragments can be present in fluids like blood plasma or urine, depending on the sample collected. The measurement helps identify specific genetic material that may relate to skin health or disease processes.

Why Might Your Doctor Order This Test?

Your doctor may recommend this test to screen for genetic mutations, monitor skin conditions, or investigate abnormal cell shedding. It could also be part of a broader evaluation for hereditary disorders or cancer research.

Sample Collection and Preparation

The test typically uses a fluid sample, such as plasma (from blood) or urine. Your healthcare provider will explain the process and ensure proper handling to preserve DNA integrity for accurate results.

What Does a Result Mean?

Results are qualitative (present/absent) or quantitative, depending on the probe used. Elevated or altered DNA levels may indicate abnormal cell activity, genetic predispositions, or conditions affecting skin or systemic health. Interpretation depends on clinical context and comparison with known reference ranges or research standards.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test may play a role in detecting early genetic markers for skin cancers, hereditary disorders, or inflammatory conditions. It could also support research into cellular turnover, genetic mutations, or biomarkers for monitoring chronic skin diseases. However, it is not a standard diagnostic tool for most conditions and is often used in specialized or investigational settings.

Short name

DNA from skin cells in body fluids (screening)

Frequently asked questions

What are the possible causes for abnormal results?
Abnormal DNA levels may suggest conditions like skin cancer (e.g., melanoma or squamous cell carcinoma), genetic syndromes affecting skin cells, or systemic diseases causing excessive cell shedding. It could also reflect normal variations in DNA presence depending on the sample type or individual health status.
How often is this test repeated, and when would follow-up be needed?
Repetition depends on clinical need. If this test is part of monitoring a known condition, follow-up may occur at intervals recommended by your doctor. If results are abnormal, further testing or evaluation by a specialist may be required to determine next steps.
Are there any risks or side effects associated with this test?
The test involves a standard blood draw or urine collection, which carries typical risks such as mild bruising, discomfort, or infection at the sample site. No additional risks are associated with the DNA analysis itself, but proper handling of the sample is critical for accurate results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy