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Epidermal keratin DNA (quantitative) in urine using a probe-based assay

Published: August 9, 2026Updated: August 16, 2026

This test measures the presence of DNA from the outer layer of skin cells (epidermal keratin) in your urine. It may be used to assess kidney function or detect certain conditions affecting the skin or urinary system.

Quick summary

["This test helps monitor kidney health or identify skin-related disorders by detecting shed skin cells in urine."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
99030-9
Short code
S epidermidis DNA Ur Ql NAA+probe
Synonyms
S epidermidis DNA Ur Ql NAA+probe
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like kidney problems (such as protein in urine), skin conditions (like psoriasis or eczema), or if you’re undergoing treatment for conditions that could affect skin cell shedding. It can also be part of a broader evaluation for urinary tract issues or kidney disease.

What to Expect Before the Test

No special preparation is needed. You’ll likely provide a urine sample in a clean container, similar to a routine urine test. Avoid excessive exercise or strenuous activity 24 hours before testing to ensure accurate results.

What the Test Results Mean

Results may indicate normal shedding of skin cells, potential kidney dysfunction, or conditions affecting skin turnover. Elevated levels could signal kidney problems, urinary tract infections, or certain dermatological conditions. Your provider will interpret results in the context of your overall health.

Common Conditions Monitored or Diagnosed

This test may help diagnose or monitor conditions like chronic kidney disease, urinary tract infections, or skin disorders such as psoriasis. It can also assist in evaluating kidney function in patients with unexplained proteinuria or hematuria.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated epidermal keratin DNA in urine can signal kidney issues, such as glomerular damage, where the kidneys filter blood improperly. It may also reflect urinary tract inflammation or infection. For skin-related conditions, increased shedding could correlate with active dermatological diseases, though further testing would confirm diagnosis. This test is not a standalone diagnostic for skin disorders but supports broader evaluations.

Short name

Urine Epidermal Keratin DNA Probe Test

Frequently asked questions

What does a positive or abnormal result mean?
An abnormal result may suggest kidney problems, urinary tract infection, or excessive skin cell shedding. Your provider will discuss findings with you and may recommend additional tests or treatments based on your symptoms and medical history.
Is this test painful or uncomfortable?
No, this test involves a simple urine sample collection. There’s no discomfort, and you can collect the sample at home or in a lab setting.
How often can I expect to have this test?
Frequency depends on your healthcare provider’s orders. Some patients may need it periodically to monitor kidney function or skin conditions, while others may only need it once for diagnostic purposes.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy