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Serum Anti-Septin 5 Immunoglobulin G (IgG) Antibody

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of antibodies against a protein called septin 5 in your blood. These antibodies may be present if your immune system is responding to an unusual exposure or condition involving this protein.

Quick summary

["This test helps evaluate potential autoimmune or inflammatory responses related to septin 5."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
101463-8
Short code
Septin-5 IgG SerPl Ql CBA IFA
Synonyms
Septin-5 IgG SerPl Ql CBA IFA
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0.8
Ref high
1.2
Critical range
— – 5 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
cba-ifa
CPT
85610
SNOMED
396252006
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Might This Test Be Ordered?

Your healthcare provider may recommend this test if you have symptoms or conditions linked to immune system activity involving septin 5, such as certain autoimmune diseases or unexplained chronic inflammation. It may also be part of a broader diagnostic workup for suspected autoimmune disorders or to monitor immune responses in research or clinical trials.

What Does This Test Measure?

The test detects the presence and concentration of IgG antibodies specific to septin 5 in your serum. Septin 5 is a protein involved in cell structure and function, and its role in disease is still being studied. Elevated levels of these antibodies could indicate an immune response, though they may not always correlate directly with disease activity.

Sample Collection and Preparation

A blood sample is drawn from a vein in your arm. The blood is then processed to separate serum, which is the liquid part containing the antibodies being tested. This serum is sent to a laboratory for analysis using an immunoassay method.

What to Expect Before the Test

No special preparation is typically required for this test. You may continue with your usual activities, but avoid heavy exercise or consuming alcohol 24 hours before the blood draw if instructed by your provider.

Reference range

INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A

Specimen: serum

Inform your healthcare provider if you are taking blood thinners. No special preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

IgG Antibody to Septin 5

Frequently asked questions

What does a positive or elevated result mean?
A positive or elevated result indicates the presence of IgG antibodies against septin 5. This could mean your immune system is actively producing these antibodies, which may or may not be directly linked to a specific disease. Your healthcare provider will discuss the results with you and may recommend additional testing or monitoring.
Could this test be used to diagnose a specific disease?
Currently, this test is not routinely used to diagnose specific diseases. It may be part of a broader diagnostic evaluation, especially in research settings or for conditions suspected to involve immune responses to septin 5. Your provider will guide whether this test is appropriate for your situation.
How often would I need this test?
The frequency of this test depends on your medical condition, symptoms, and treatment plan. Your healthcare provider will determine how often to repeat the test based on your individual needs and response to treatment.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy