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Serum or Plasma Anti-Septin 7 Immunoglobulin G (IgG) Level

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of antibodies (specifically Immunoglobulin G, or IgG) directed against Septin 7 in your blood. Septin 7 is a protein involved in cell structure and function, and antibodies against it may be detected in certain autoimmune or inflammatory conditions.

Quick summary

["This test helps evaluate immune responses related to Septin 7, which may be important in diagnosing or monitoring certain autoimmune or systemic diseases."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
108793-1
Short code
Septin-7 IgG Msmt SerPl
Synonyms
Septin-7 IgG Msmt SerPl
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0.8
Ref high
1.2
Critical range
— – 5 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
85610
SNOMED
396252006
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if they suspect an autoimmune condition, such as systemic lupus erythematosus (SLE) or other connective tissue disorders, where antibodies against specific proteins (autoantibodies) are known to play a role. It could also be part of a broader evaluation for unexplained symptoms like chronic fatigue, joint pain, or other systemic symptoms.

What to Expect Before the Test

No special preparation is typically needed for this test. You may have a blood sample drawn from a vein in your arm, similar to other blood tests. If you are on blood thinners or have a history of bleeding disorders, let your provider know before the test.

What the Test Results Mean

The test measures the concentration of IgG antibodies against Septin 7 in your blood. While elevated levels may suggest an immune response, such as in autoimmune conditions, normal levels do not definitively rule out these conditions. Results should be interpreted by your healthcare provider in the context of your overall health and symptoms.

Common Conditions Monitored

This test may be used to monitor or diagnose conditions where autoantibodies against Septin 7 are suspected, such as certain autoimmune rheumatic diseases. It is not a standalone test but may be part of a comprehensive evaluation.

Reference range

INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A

Specimen: serum

Inform your healthcare provider if you are taking blood thinners. No special preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Anti-Septin 7 IgG

Frequently asked questions

What does a positive result mean?
A positive result (detected antibodies) suggests your immune system may be producing antibodies against Septin 7. This could be part of an autoimmune process, but it does not definitively diagnose a specific condition. Your healthcare provider will discuss the results with you and may recommend additional tests or treatments based on your symptoms and overall health.
Can this test be used to diagnose lupus or another autoimmune disease?
No, this test alone is not used to diagnose lupus or other autoimmune diseases. It is often included as part of a broader panel of tests to help identify potential autoimmune activity. Other tests, such as blood counts, inflammatory markers, or other autoantibody panels, are usually needed for a comprehensive evaluation.
How often should I get this test if I have an autoimmune condition?
The frequency of testing depends on your specific condition, symptoms, and treatment plan. Your healthcare provider will determine how often to monitor this test or other related markers based on your individual needs. Regular follow-ups with your doctor are essential to manage your condition effectively.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy