Serum Ammonia Concentration
This test measures the amount of ammonia, a waste product, in your blood serum. Ammonia is produced when proteins break down in your body.
["Ammonia levels can help diagnose liver or kidney issues or monitor certain medical conditions."]
Key facts at a glance
- LOINC
- 27223-7
- Short code
- Serine Amn-sCnc
- Synonyms
- Serine Amn-sCnc
- Category
- chemistry
- Sample
- fluid
- Container
- Sterile tube
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 2-5 mL
- Stability
- Room temperature: 2h, Refrigerated: 24h
- Hemolysis max
- 300
- TAT
- 4–24 hours
- Order
- routine
Why This Test Is Done
Your healthcare provider may order a serum ammonia test if you have symptoms like confusion, fatigue, or trouble breathing. It’s also used to check for liver disease, kidney problems, or metabolic disorders. Sometimes, it’s done before or after surgery, especially if you have a history of liver or kidney issues.
What to Expect Before the Test
You’ll likely have a small needle inserted into your arm or vein to draw blood. The process is quick and usually painless. Avoid eating or drinking for a few hours before the test if your provider recommends it, as food can affect ammonia levels.
What the Results Mean
High ammonia levels may indicate problems with your liver or kidneys, which can’t properly remove waste from your blood. Low levels might suggest certain metabolic disorders or overmedication with drugs that lower ammonia. Your provider will discuss these results with you in detail.
Common Conditions Monitored
This test is often used to monitor liver diseases (like cirrhosis), kidney failure, or conditions affecting how your body processes proteins. It can also help track how well treatments for these conditions are working.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
Serum Ammonia
Frequently asked questions
What causes high ammonia levels?
What causes low ammonia levels?
How often should this test be done?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy