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Serum Free Serum Ferritin (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of ferritin in your blood that is not bound to proteins, providing insight into your iron stores.

Quick summary

["Free ferritin helps assess iron deficiency or overload beyond what standard ferritin tests show."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
47744-8
Short code
Serine SFr CSF
Synonyms
Serine SFr CSF
Category
chemistry
Sample
csf
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms of iron-related conditions, such as fatigue, anemia, or unexplained low iron levels. It could also be used to monitor iron status in patients with chronic diseases or those undergoing treatments affecting iron metabolism.

What to Expect Before the Test

No special preparation is needed for this test. You may have a blood draw, typically from a vein in your arm. If you’re on blood thinners or have a history of bleeding, let your provider know.

What the Results Mean

Free ferritin levels alone don’t provide a direct reference range, but they can help evaluate iron stores when combined with other tests. High levels may suggest chronic iron overload, while low levels may indicate iron deficiency.

Common Conditions Monitored

This test is often used in patients with hemochromatosis (iron overload), hemolytic anemia, or those receiving blood transfusions. It may also help assess iron status in people with liver disease or inflammatory conditions.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Free Serum Ferritin

Frequently asked questions

What causes elevated free ferritin levels?
Elevated free ferritin can result from chronic inflammation, liver disease, certain cancers, or genetic conditions like hemochromatosis. It may also appear in people with hemolytic anemia or those receiving frequent blood transfusions.
What causes low free ferritin levels?
Low free ferritin is commonly associated with iron deficiency, malnutrition, or conditions that increase iron loss (e.g., heavy menstrual bleeding or gastrointestinal bleeding). It may also be seen in patients with chronic kidney disease.
How often should this test be repeated?
The frequency depends on your medical condition. If you have an ongoing iron-related issue, your provider may recommend retesting every few months or as needed to monitor changes in your iron status.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy