Serum/plasma protein electrophoresis with bromocresol purple (BCP) dye binding assay
This test measures the distribution of proteins in your blood, separated by size and charge, using a dye that binds to specific protein groups. It helps identify patterns that may indicate conditions like kidney disease, liver problems, or certain cancers.
["This test helps doctors spot unusual protein patterns that could signal health issues."]
Key facts at a glance
- LOINC
- 111526-0
- Short code
- SerPl LC/MS/MS
- Synonyms
- SerPl LC/MS/MS
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- lc-ms-ms
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What Proteins Does This Test Measure?
Electrophoresis separates blood proteins into five main zones: albumin, alpha-1 globulins, alpha-2 globulins, beta globulins, and gamma globulins (antibodies). Each zone reflects different protein functions, such as transport, immune response, or fluid balance. Abnormal patterns may suggest conditions like multiple myeloma, cirrhosis, or chronic inflammation.
How Is the Sample Collected?
A blood sample is drawn from a vein, usually in your arm. The blood is then processed to separate serum or plasma for testing. No special preparation is needed, but fasting may be advised depending on your doctor’s instructions.
Why Might This Test Be Ordered?
Doctors order this test to investigate symptoms like unexplained weight loss, fatigue, swelling, or changes in kidney/liver function. It’s also used to monitor conditions like autoimmune diseases, infections, or cancers that affect protein levels.
What Could Abnormal Results Mean?
Results may show shifts in protein bands, such as elevated gamma globulins (indicating immune disorders) or low albumin (suggesting liver/kidney disease). Always discuss results with your healthcare provider, as patterns vary widely.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
This test plays a key role in diagnosing and managing conditions affecting protein metabolism. For example, elevated gamma globulins may point to monoclonal gammopathy (e.g., multiple myeloma), while abnormal albumin levels can signal protein-losing syndromes or organ dysfunction. Early detection helps guide treatment plans.
Short name
Protein Electrophoresis (BCP)
Frequently asked questions
What does a protein electrophoresis test measure exactly?
Do I need to fast before this test?
How long does it take to get results from this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy