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Serum or plasma mass concentration of glycine

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of glycine, an amino acid found in your blood. Glycine plays a role in protein synthesis, metabolism, and other bodily functions.

Quick summary

["Understanding your glycine levels may help assess metabolic health or conditions related to amino acid balance."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
31666-1
Short code
SGPG IgM Ser-aCnc
Synonyms
SGPG IgM Ser-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Glycine Does in Your Body

Glycine is involved in creating proteins, transmitting nerve signals, and supporting energy production in cells. Your body naturally produces glycine, but certain conditions or medical treatments may affect its levels.

Why This Test Might Be Ordered

Your healthcare provider may order this test if you have symptoms like fatigue, muscle weakness, or signs of metabolic disorders. It could also be part of a broader evaluation for conditions like glycine encephalopathy or other amino acid imbalances.

What to Expect Before the Test

No special preparation is typically needed. You may fast for 8–12 hours before the test if instructed, but always follow your provider’s instructions. Bring any medications or supplements you’re taking to your appointment.

During the Test

A healthcare professional will draw blood from a vein in your arm. You may feel a slight pinch or discomfort, but it usually lasts only a few seconds. The process takes about 5–10 minutes.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Glycine Level

Frequently asked questions

How long does it take to get results?
Results are usually available within 1–3 business days, depending on your lab’s processing time. Your healthcare provider will discuss the findings with you during your follow-up visit.
What causes glycine levels to change?
Several factors may influence glycine levels, including diet (especially protein intake), certain medications, liver or kidney disease, genetic conditions, or metabolic disorders. Stress, illness, or dehydration can also play a role.
Can I adjust my diet to affect glycine levels?
While diet can influence amino acid metabolism, glycine levels are primarily regulated by your body’s natural processes. If you suspect dietary factors are affecting your results, discuss this with your provider before making significant changes.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy