D-dimer (Plasma) – Quantitative Measurement
This test measures the level of D-dimer, a breakdown product of a blood-clotting protein, to help assess whether you may have had a clot that has since dissolved.
["D-dimer helps rule out blood clots or help guide treatment decisions."]
Key facts at a glance
- LOINC
- 55398-2
- Short code
- Short Fibrin D-dimer FEU & DDU Pnl PPP
- Synonyms
- Short Fibrin D-dimer FEU & DDU Pnl PPP
- Category
- coagulation
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 86430
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What Is D-Dimer Used For?
D-dimer is primarily used to evaluate the risk of blood clots (thrombosis) or disseminated intravascular coagulation (DIC), a rare but serious condition where clots form throughout the body. It can also assist in diagnosing conditions like pulmonary embolism (blockage in the lungs) or deep vein thrombosis (clot in a vein).
How Is the Test Performed?
A small blood sample is drawn from a vein, usually in your arm. The blood is processed to separate plasma, where the D-dimer levels are measured using a sensitive immunoassay technique.
What Does a High or Low Level Mean?
Elevated D-dimer levels often suggest recent clot formation or breakdown, which may indicate conditions like a pulmonary embolism or deep vein thrombosis. However, false positives can occur due to pregnancy, surgery, or other inflammatory conditions. Low or normal levels generally mean there is less likelihood of active clotting, but they don’t rule out all clot-related issues entirely.
When Might You Need This Test?
Your healthcare provider may order a D-dimer test if you have symptoms like shortness of breath, chest pain, leg swelling, or if you’ve had recent surgery, trauma, or a history of blood clots.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
D-dimer plays a key role in diagnosing and managing conditions involving abnormal blood clotting or clot breakdown. It helps narrow down potential causes and supports treatment decisions, such as anticoagulant therapy for blood clots.
Short name
D-Dimer
Frequently asked questions
Why might my D-dimer test result be higher than expected?
Can a low D-dimer level mean I don’t have a blood clot?
How long does it take to get my D-dimer test results?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy