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Serum or plasma concentration of sialic acid

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of sialic acid, a type of sugar found in certain body fluids, including blood. It may be used to assess metabolic or biochemical conditions affecting these sugars.

Quick summary

["Sialic acid levels can help diagnose or monitor metabolic disorders linked to sugar metabolism."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
75045-5
Short code
Sialate Amn-sCnc
Synonyms
Sialate Amn-sCnc
Category
chemistry
Sample
fluid
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
2-5 mL
Stability
Room temperature: 2h, Refrigerated: 24h
Hemolysis max
300
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test if you have symptoms or conditions that could be linked to abnormal sialic acid levels, such as certain genetic metabolic disorders (e.g., sialidosis). It may also be part of a broader evaluation for unexplained biochemical imbalances or inherited metabolic diseases.

What Does the Test Involve?

A blood sample is taken from a vein in your arm. The blood is then processed to separate serum or plasma, where sialic acid levels are measured using a specialized laboratory technique.

What to Expect Before the Test

No special preparation is typically required, but you may be asked to fast for a few hours if instructed by your provider. Wear comfortable clothing and plan to rest for a short time after the draw.

What to Expect During the Test

You’ll lie down comfortably while a healthcare professional inserts a small needle into your arm. You may feel a slight pinch, but the procedure usually takes just a few minutes. A bandage will cover the site afterward.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated or low sialic acid levels may indicate inherited metabolic disorders, such as sialidosis, which can affect organs like the liver, kidneys, or nervous system. Abnormal results may prompt further testing or genetic counseling to determine the cause and appropriate treatment.

Short name

Sialic Acid Level

Frequently asked questions

What are the possible causes of abnormal results?
Abnormal sialic acid levels can result from genetic metabolic disorders (e.g., sialidosis), certain medications, or conditions affecting sugar metabolism. Your provider will discuss these findings with you and may recommend additional tests or lifestyle adjustments.
How long will it take to get my results?
Results are typically available within 1 to 3 business days, depending on your lab’s processing schedule. Your healthcare provider will contact you to discuss the results once they are ready.
Can diet or lifestyle affect this test?
Dietary changes alone are unlikely to significantly impact sialic acid levels, but fasting may be necessary if your provider directs it. Avoiding certain medications or supplements for a few days before testing can also help ensure accurate results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy