C-reactive protein (high-sensitivity) by nephelometry

What Is hsCRP Used For?

hsCRP (high-sensitivity C-reactive protein) is typically ordered to evaluate the risk of heart disease, monitor chronic conditions like arthritis or inflammatory bowel disease, or assess response to treatments that target inflammation. It’s also used in research settings to study inflammation in more detail than standard CRP tests.

How Is This Test Done?

A blood sample is drawn from a vein, usually in your arm. The blood is sent to a lab where it’s analyzed using nephelometry, a method that measures how much light scatters when the protein binds to antibodies. Results are reported in milligrams per liter (mg/L).

What Does a High or Low Result Mean?

Results don’t have a single ‘normal’ range because they vary by health status, age, and other factors. A higher hsCRP level may indicate increased inflammation, which could raise concerns about heart disease or other inflammatory conditions. A very low level might suggest minimal inflammation, but it doesn’t rule out other causes.

How Often Is This Test Needed?

Your doctor may order hsCRP periodically if you have a history of heart disease, diabetes, or autoimmune conditions. Some guidelines recommend testing every few years for adults at higher cardiovascular risk, but frequency depends on your specific health plan and needs.