Skip to content

Serum or Plasma IgG Substance Concentration (Qualitative or Quantitative)

Published: August 9, 2026Updated: August 17, 2026

This test measures the amount of Immunoglobulin G (IgG), a type of antibody in your blood. IgG is the most common antibody and plays a key role in fighting infections and diseases.

Quick summary

["IgG helps your immune system defend against bacteria and viruses, and it’s important for long-term immunity."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
102867-9
Short code
Silver Birch IgG RAST
Synonyms
Silver Birch IgG RAST
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
10
Ref high
40
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
rast
CPT
84484
SNOMED
302774002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What IgG Tests Measure

IgG tests determine the concentration of IgG antibodies in your blood, either as a screening or confirmatory test. The method used may vary, but it often involves detecting the presence or level of IgG through techniques like immunoassay or nephelometry. This helps assess immune function, diagnose conditions like immunodeficiency, or monitor treatment responses.

Why It Matters in Your Health

IgG levels can indicate whether your immune system is functioning properly. Low levels may suggest immune deficiencies, while abnormal levels could point to infections, autoimmune diseases, or other health issues. Your doctor may order this test if you have frequent infections, unexplained fatigue, or symptoms of immune disorders.

When You Might Need This Test

You might need an IgG test if you have symptoms like repeated infections, slow wound healing, or if your doctor suspects an immune-related condition. It’s also used in newborns to check for maternal antibodies passed during pregnancy or after birth.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the test if it involves a blood draw. Wear comfortable clothing and arrive with an ID for easy access to your medical records.

Reference range

Adult: 10-40 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance of IgG Levels

Short name

IgG Level (Serum/Plasma)

Frequently asked questions

How long does it take to get IgG test results?
Results are typically available within 1–3 business days, depending on your lab’s processing time. Your doctor will discuss the findings with you during your follow-up visit.
Can IgG levels change with age?
Yes, IgG levels can vary with age. Infants and young children may have lower IgG levels compared to adults, and certain conditions or treatments can temporarily alter them. Your doctor will interpret results in the context of your overall health and medical history.
What does it mean if my IgG test is abnormal?
Abnormal IgG levels may signal an immune disorder, chronic infection, or other health issues. Your doctor will review the results with you and may recommend further testing or treatments based on the cause, such as immune therapy or monitoring for infections.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy