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Silver and Creatinine, 24-Hour Urine

Published: August 9, 2026Updated: August 16, 2026

Measures the amount of silver excreted in urine over 24 hours, with urine creatinine used to help account for differences in urine concentration.

Quick summary

["This test can help evaluate recent exposure to silver by measuring silver in a complete 24-hour urine collection."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
29978-4
Short code
Silver/Creat 24h Ur
Synonyms
Silver/Creat 24h Ur
Category
kidney
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

This test measures silver in urine collected for 24 hours. Creatinine, a waste product normally found in urine, may also be measured to help interpret the silver result.

Why might I need this test?

Urine testing may be used to assess exposure to silver in people who work with silver-containing materials or have had possible contact with silver. The results may be used alongside exposure history and other clinical findings.

How is the test performed?

You collect all urine for a full 24-hour period using the container and instructions provided by the laboratory. The collected sample is then analyzed to determine the amount of silver and, when appropriate, creatinine.

How do I prepare for the test?

Follow the laboratory's collection instructions carefully, including the starting time, ending time, and any container-handling requirements. Missing urine or spilling part of the collection can make the results less reliable.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

A higher-than-expected urine silver level may indicate recent or ongoing exposure to silver. Low levels generally mean little silver was excreted during the collection period. Interpretation should consider workplace exposure, symptoms, medications, and the adequacy of the 24-hour collection.

Short name

24-Hour Urine Silver and Creatinine

Frequently asked questions

What does a 24-hour urine test show?
It measures the total amount of a substance, such as silver, released in urine over one full day. This can be more representative than a single urine sample.
Why is creatinine measured with urine silver?
Creatinine is a marker of urine production and can help account for differences in urine concentration. This makes it easier to compare silver results appropriately.
Does an elevated result mean I have silver poisoning?
Not necessarily. An elevated result suggests increased silver exposure or excretion, but a clinician must interpret it with your exposure history, symptoms, and other tests.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy