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Pancreatic Enzyme Panel (Fecal)

Published: August 9, 2026Updated: August 17, 2026

This test measures enzymes produced by your pancreas to help assess digestive function. Low levels may indicate pancreatic insufficiency or other digestive issues.

Quick summary

["This test checks if your pancreas is working properly to help digest food."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
111994-0
Short code
Site Pancreas Endscpy
Synonyms
Site Pancreas Endscpy
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Critical range
0.5 N/A – —
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
endoscopy
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may recommend this test if you have symptoms like unexplained weight loss, chronic diarrhea, or steatorrhea (fatty stools). It can also be used to monitor pancreatic function in people with known pancreatic disorders or after pancreatic surgery.

What to Expect Before the Test

No special preparation is needed. You’ll provide a sample of your stool, which is collected in a container. Follow your healthcare provider’s instructions for collection.

What the Test Results Mean

Results are compared to typical values for healthy individuals. Low enzyme levels suggest pancreatic insufficiency, while normal or high levels may indicate other digestive or gastrointestinal conditions.

Common Conditions This Test Helps Diagnose

This test may help diagnose conditions like cystic fibrosis, chronic pancreatitis, pancreatic cancer, or other pancreatic diseases that affect digestion.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test is important for identifying pancreatic insufficiency, which can lead to malnutrition or malnutrition-related complications. Early detection allows for better management and treatment options.

Short name

Fecal Pancreatic Enzyme Test

Frequently asked questions

What causes low pancreatic enzyme levels in this test?
Low levels can be caused by pancreatic diseases (e.g., chronic pancreatitis), pancreatic cancer, cystic fibrosis, or other conditions that impair pancreatic function.
How often should this test be repeated?
Your doctor will determine the frequency based on your symptoms, medical history, and test results. Follow-up may be needed if initial results are abnormal or if symptoms persist.
Can diet affect this test?
Dietary changes, such as high-fat meals, may temporarily influence enzyme levels. Your doctor may advise avoiding high-fat foods for 24–48 hours before testing to get more accurate results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy