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Skin gas analysis (partial pressure of gases in exhaled breath)

Published: August 9, 2026Updated: August 16, 2026

This test measures specific gases in the air you exhale to assess lung function and metabolic health.

Quick summary

["Helps diagnose respiratory or metabolic conditions by analyzing breath composition."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
104834-7
Short code
Skin IgA Ser Ql Human split skin sub
Synonyms
Skin IgA Ser Ql Human split skin sub
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
1.5
Ref high
9
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
human-split-skin-substrate
CPT
83002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

Your breath sample is analyzed for key gases, including carbon monoxide (CO), nitrogen oxides (NO), and other biomarkers. These gases reflect lung ventilation, oxygen exchange, and metabolic processes. The test often includes partial pressures of oxygen (pO₂), carbon dioxide (pCO₂), and potentially other gases like methane or hydrogen sulfide, depending on clinical focus. Results may be compared to baseline or reference values specific to your health status.

How Is the Test Performed?

You will exhale into a specialized breath collection device for a few minutes. The device captures and analyzes the gases in your exhaled air. No fasting or special preparation is typically required, but follow any specific instructions your healthcare provider gives you. The test is usually quick and painless.

Why Might This Test Be Ordered?

Your doctor may recommend this test to evaluate lung function, detect metabolic disorders, or monitor conditions like chronic obstructive pulmonary disease (COPD), cystic fibrosis, or diabetes. It can also help assess exposure to environmental toxins or identify abnormalities in lung ventilation.

What Are Common Findings?

Abnormal gas levels may indicate issues such as poor lung function, metabolic imbalances, or infections. For example, elevated carbon dioxide levels might suggest hyperventilation or respiratory obstruction, while unusual nitrogen oxide levels could point to inflammation or infection in the lungs.

Reference range

Follicular: 1.5-9.0 mIU/mLN/A

Specimen: serum

For females: inform if menstrual cycle status. For certain tests, timing within menstrual cycle may matter.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Frequently asked questions

Why do I need to know my breath gas levels?
Breath gas analysis provides a non-invasive way to monitor lung health and metabolic function. It can help detect early signs of respiratory or metabolic conditions that might not show up on traditional blood tests alone. This test is particularly useful for patients with chronic lung diseases or those undergoing treatment for metabolic disorders.
How long will it take to get my results?
Results are typically available within a few days to a week, depending on your lab and healthcare provider. Your doctor will discuss the findings with you during your follow-up visit.
Can I eat or drink before this test?
Generally, no special preparation is needed. However, avoid smoking or consuming strong-smelling foods (like garlic or onions) for a few hours before the test, as these can interfere with the results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy