Serum Immunoglobulin G (IgG) Profile (Electrophoresis)
This test measures the different types of proteins in your blood, including IgG, which is the most common antibody in your immune system. It helps assess how your immune system is functioning and identify any abnormalities in protein distribution.
["This test helps diagnose and monitor immune system conditions and protein disorders."]
Key facts at a glance
- LOINC
- 66881-4
- Short code
- Skin IgG Ser Ql Monkey esoph
- Synonyms
- Skin IgG Ser Ql Monkey esoph
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 7.35
- Ref high
- 7.45
- Critical range
- 7.2 N/A – 7.6 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- monkey-esophagus-substrate
- CPT
- 82784
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What Does This Test Measure?
The IgG electrophoresis test separates blood proteins into fractions using an electric field. This includes IgG, IgA, IgM, albumin, and other proteins. IgG is the primary antibody that helps fight infections and diseases. The test can show if there’s an excess or deficiency of these proteins, which may indicate conditions like immune disorders, infections, or certain cancers.
Why Might You Need This Test?
Your healthcare provider may order this test if you have symptoms like frequent infections, unexplained fatigue, swelling, or if they suspect conditions such as immunodeficiency, multiple myeloma, or other protein-related disorders. It can also be used to monitor treatment progress for conditions like lupus or other autoimmune diseases.
Sample Collection and Preparation
A blood sample is drawn from a vein, usually in your arm. The blood is then processed to separate the serum (liquid part without clots) for analysis. No special preparation is needed, but fasting may be advised depending on other tests ordered together.
Common Conditions Monitored or Diagnosed
This test can help diagnose or monitor conditions such as primary immunodeficiency diseases, infections, inflammatory diseases, and certain cancers like multiple myeloma. It may also be used to check for protein-losing syndromes or other metabolic disorders.
Reference range
NCBI: pH 7.35-7.45N/A
No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
This test provides critical information about the balance of proteins in your blood, which is essential for immune function and overall health. Abnormal results may indicate an underlying issue that requires further medical evaluation, such as an immune disorder, infection, or a blood-related condition.
Short name
IgG Electrophoresis
Frequently asked questions
What Are the Normal Results?
How Long Does It Take to Get Results?
Can I Eat or Drink Before This Test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy