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Genetic analysis for a deletion mutation in the SLC25A15 gene (related to mitochondrial carrier function)

Published: August 9, 2026Updated: August 16, 2026

This test checks for a specific genetic change in the SLC25A15 gene, which may affect how certain molecules are transported inside your cells.

Quick summary

["A genetic mutation in SLC25A15 could impact energy production and metabolic processes."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
94717-6
Short code
SLC25A15 c.562_564delTTC Geno Bld/T
Synonyms
SLC25A15 c.562_564delTTC Geno Bld/T
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
molgen
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What This Test Measures

The test identifies a deletion in the SLC25A15 gene, which encodes a protein involved in mitochondrial function. Mitochondria are the energy powerhouses of cells. This mutation may disrupt normal transport processes within these organelles, potentially affecting energy metabolism.

Why It Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms or a family history suggestive of mitochondrial disorders, metabolic diseases, or conditions linked to impaired mitochondrial function. It could also be part of a broader genetic evaluation.

How the Test Works

A small sample of your blood (whole blood) is collected and analyzed to detect the specific deletion in the SLC25A15 gene. Genetic testing involves examining DNA sequences to identify structural changes like deletions.

What the Results Mean

Results will indicate whether the deletion is present in your DNA. If found, it may suggest an increased risk for mitochondrial-related conditions, though symptoms can vary widely and may not appear immediately.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Genetic mutations in SLC25A15 can lead to mitochondrial dysfunction, potentially causing metabolic disorders, neurological issues, or developmental delays. Early identification can help guide management strategies and family planning.

Short name

SLC25A15 Gene Deletion Test

Frequently asked questions

What does a positive result mean?
A positive result means the deletion mutation is present in your DNA. This may raise concerns about potential mitochondrial-related health risks, but it does not definitively diagnose a condition. Your healthcare provider will discuss next steps, including genetic counseling and potential monitoring.
Will this test affect my insurance coverage?
Whether this test is covered depends on your insurance plan, medical necessity, and local healthcare policies. Always confirm with your insurer or healthcare provider before undergoing testing.
Can I get this test if I’m not symptomatic?
Yes, this test may be recommended as part of a genetic evaluation for family planning, risk assessment, or if you have a family history of mitochondrial disorders. Always discuss with your healthcare provider to determine the best approach for you.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy