Cystatin C, Serum Concentration (Quantitative)
This test measures the level of cystatin C, a protein produced by all cells in the body. It helps assess kidney function and can be useful in monitoring chronic kidney disease.
["Cystatin C is a simple blood test to check kidney health."]
Key facts at a glance
- LOINC
- 53724-1
- Short code
- SLC26A4 p.T416P Bld Ql
- Synonyms
- SLC26A4 p.T416P Bld Ql
- Category
- chemistry
- Sample
- whole-blood
- Container
- Lavender-top (EDTA)
- Units
- N/A
- Ref low
- 4.5
- Ref high
- 12
- Critical range
- — – 5 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- molgen
- CPT
- 85610
- SNOMED
- 396252006
- Specimen volume
- 3 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
Why Is This Test Done?
Your healthcare provider may order this test if you have symptoms of kidney problems, such as fatigue, swelling, or frequent urination. It’s also used to monitor kidney function in people with diabetes, high blood pressure, or other conditions that can affect the kidneys over time. Sometimes, it’s used alongside other tests to better evaluate kidney function, especially in cases where traditional kidney function tests (like creatinine) might not be reliable.
How Is the Test Performed?
A small blood sample is taken from a vein, usually in your arm. The blood is sent to a lab where it is analyzed to measure cystatin C levels. The result is typically available within a few days.
What Do the Results Mean?
Higher than expected cystatin C levels may indicate kidney problems, including reduced kidney function. Lower levels might suggest other health conditions or medications that affect protein production. Your healthcare provider will interpret the results in the context of your overall health and other tests.
Common Causes of Abnormal Results
Elevated cystatin C levels can be caused by kidney disease, infections, muscle disorders, or certain medications. Lower levels may be linked to conditions that reduce protein production or certain genetic factors. Always discuss any changes in your results with your doctor.
Reference range
Adult: 4.5-12.0 μg/dLN/A
Take your thyroid medication after the blood draw if applicable. No fasting required.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
Cystatin C
Frequently asked questions
What if I have questions about my results?
How often should I get this test?
Can I eat or drink anything before the test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy