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Serum or Plasma Creatinine Concentration (Substance Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of creatinine, a waste product from muscle metabolism, in your blood. It helps assess how well your kidneys are filtering blood.

Quick summary

["Kidney function check via creatinine levels."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
110747-3
Short code
SLEV IgM Msmt Ser
Synonyms
SLEV IgM Msmt Ser
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order this test to evaluate kidney health, diagnose kidney disease, or monitor kidney function in people with conditions like diabetes or high blood pressure. It’s also used to check how well dialysis is working or to guide treatment decisions for certain medications.

What to Expect Before the Test

No special preparation is needed, but you may be asked to fast for 8–12 hours before the test if it’s part of a broader metabolic panel. Drink plenty of water the day before to help dilute urine if you’re having a urine-based test (though this test is blood-based).

What Happens During the Test?

A healthcare provider will draw a small amount of blood from a vein, usually in your arm. The process is quick and typically painless. You may feel a slight pinch or sting, but it usually doesn’t cause long-term discomfort.

What Are the Results Mean?

Higher than expected levels may indicate poor kidney function, while lower levels could suggest overhydration, muscle breakdown, or other conditions. Your doctor will interpret results in relation to your overall health and medical history.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Creatinine levels are a key marker for kidney function because it’s directly linked to how well blood is filtered. Elevated levels often signal reduced kidney function, which can be an early sign of kidney disease. It’s also used alongside other tests (like blood urea nitrogen) to assess kidney health and guide treatment plans for chronic conditions.

Short name

Creatinine

Frequently asked questions

What causes creatinine levels to be higher than normal?
Several factors can influence creatinine levels, including dehydration, muscle mass, certain medications, or kidney disease. If your levels are elevated, your doctor may investigate further to rule out conditions like chronic kidney disease or acute kidney injury.
What if my creatinine level is lower than expected?
Lower creatinine levels might suggest overhydration, muscle wasting, or conditions that reduce muscle mass. In some cases, it could also indicate errors in lab processing, so your doctor may repeat the test or check other factors.
How often should I get this test?
Frequency depends on your health status. People with kidney disease or risk factors (like diabetes or hypertension) may need this test every few months or annually. Your doctor will determine the best schedule for you based on your medical history and needs.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy