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Immunoassay for Antibodies to Nucleic Acid Binding Protein with Granulin Domain (NANOPRB)

Published: August 9, 2026Updated: August 16, 2026

This test measures antibodies in your blood that may react to a specific protein found in certain cells. It can help identify conditions where these proteins might be involved, though its clinical use is still being studied.

Quick summary

This test may help assess rare autoimmune or inflammatory conditions linked to NANOPRB-related proteins.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
96311-6
Short code
S lugdunensis DNA Bld Pos Ql NAA+non-prb
Synonyms
S lugdunensis DNA Bld Pos Ql NAA+non-prb
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
non-probe-amp-tar
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What This Test Measures

The test detects the presence of antibodies against NANOPRB, a protein that plays a role in cell signaling and immune regulation. These antibodies can be elevated in conditions where the immune system mistakenly targets these proteins, potentially contributing to inflammation or autoimmune responses.

Why It Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms or conditions associated with autoimmune diseases, chronic inflammation, or rare genetic disorders linked to NANOPRB. It may also be used in research or specialized diagnostic contexts.

What to Expect Before the Test

No special preparation is typically required. You may have a blood sample drawn from a vein in your arm, similar to other blood tests. If you’re on blood thinners, let your provider know before the test.

What the Results Mean

Results are qualitative (positive or negative) and indicate whether antibodies were detected. A positive result suggests the presence of these antibodies, which may warrant further evaluation by your healthcare provider.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

NANOPRB Antibody Test

Frequently asked questions

How often will I need this test?
This test is not routinely used in standard clinical practice. It may be ordered as part of a specialized diagnostic workup for rare conditions or research studies. Follow your provider’s guidance on frequency.
What are the typical reference ranges?
Since this test is qualitative, results are not expressed as numeric ranges. A positive result means antibodies were detected; a negative result means they were not.
Are there any risks or side effects from this test?
Common risks include mild bruising, soreness, or redness at the injection site. Rarely, allergic reactions or fainting may occur. If you experience severe pain or unusual symptoms, contact your provider immediately.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy