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Serum or Plasma Creatinine Concentration (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of creatinine, a waste product from muscle metabolism, in your blood or plasma. It helps assess how well your kidneys are filtering blood.

Quick summary

["A creatinine test helps check kidney function by measuring waste in your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
105798-3
Short code
S lugdunensis DNA Ct Bld +Qn NAA+prob
Synonyms
S lugdunensis DNA Ct Bld +Qn NAA+prob
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Matters

Creatinine is a byproduct of muscle breakdown and is normally filtered out of your blood by your kidneys. If your kidneys aren’t working well, creatinine levels can build up in your blood. This test is often used to monitor kidney health, especially in people with risk factors like high blood pressure, diabetes, or a family history of kidney disease.

What to Expect During the Test

You’ll typically have a small needle inserted into your arm or vein to draw blood. The test is quick and usually done in a lab setting. If you’re tested for creatinine in urine, you may need to collect a sample over a 24-hour period or provide a random urine sample.

Factors That Can Affect Results

Several factors can influence creatinine levels, including muscle mass (higher muscle mass can lead to higher levels), dehydration, certain medications, or recent exercise. If you’ve had recent surgery, trauma, or changes in diet (like eating more meat), let your healthcare provider know so they can interpret your results accurately.

Common Uses of This Test

Doctors use creatinine tests to diagnose and monitor kidney disease, track how well dialysis is working, evaluate kidney function before surgeries or procedures, and check for conditions like chronic kidney disease (CKD) or acute kidney injury (AKI).

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Creatinine Level

Frequently asked questions

What does a high creatinine level mean?
A high creatinine level often suggests that your kidneys aren’t working as well as they should, which can indicate kidney disease or damage. However, other factors like muscle mass or dehydration can also affect the results, so your doctor will consider other health information when interpreting your test.
What does a low creatinine level mean?
A low creatinine level may indicate that your kidneys are filtering blood more efficiently, but it can also be caused by factors like low muscle mass, overhydration, or certain medical conditions. Your doctor will review your overall health and other test results to understand the cause.
Can diet affect creatinine levels?
Yes, diet can influence creatinine levels. Eating a high-protein diet or consuming large amounts of meat can temporarily increase creatinine levels. Conversely, a low-protein diet may lead to lower levels. It’s best to discuss any dietary changes with your healthcare provider before or after your test.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy