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C-reactive protein (CRP) by nephelometry

Published: August 9, 2026Updated: August 16, 2026

This test measures a protein produced by your liver in response to inflammation, often used to check for low-grade inflammation or infection.

Quick summary

["Helps track subtle inflammation that may not show up in other tests."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
97635-7
Short code
S lugdunensis DNA Snv Ql NAA+n-prb
Synonyms
S lugdunensis DNA Snv Ql NAA+n-prb
Category
chemistry
Sample
fluid
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
non-probe-amp-tar
Specimen volume
2-5 mL
Stability
Room temperature: 2h, Refrigerated: 24h
Hemolysis max
300
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order a high-sensitivity CRP test to monitor conditions like heart disease risk, autoimmune disorders, or inflammation after surgery or injury. It can also help assess response to treatment for conditions like rheumatoid arthritis or inflammatory bowel disease.

What to Expect Before the Test

No special preparation is needed. You may have a small needle inserted into your arm to draw blood. If you’re concerned about pain, let your provider know.

What the Results Mean

Results are not typically given in absolute numbers but are compared to a reference range for your age and health status. Elevated levels may indicate inflammation, infection, or other health issues.

Common Conditions Monitored

High-sensitivity CRP is often used to evaluate cardiovascular risk, track autoimmune diseases, or check for signs of inflammation in chronic conditions.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: High-sensitivity CRP is a marker for systemic inflammation. While it doesn’t diagnose specific conditions, it can guide treatment decisions and monitor disease activity in conditions like atherosclerosis, inflammatory arthritis, or post-surgical healing.

Short name

CRP (High Sensitivity)

Frequently asked questions

What does a high CRP level mean?
A high CRP level suggests inflammation is present in your body, which could be due to infection, an autoimmune condition, or other health issues. Your provider will discuss results in the context of your symptoms and medical history.
Can I eat or drink before this test?
You can eat and drink normally before this test. Blood is drawn from a vein in your arm, and no fasting is required.
How often will I need this test?
Frequency depends on your condition and treatment plan. Your provider will let you know how often this test should be done, such as every few months or annually.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy